3-(3-phenyl-1,2,4-oxadiazol-5-yl)propionic acid prop-2-ynyl ester

Base Information

• Chemical Name: 3-(3-phenyl-1,2,4-oxadiazol-5-yl)propionic acid prop-2-ynyl ester
• CAS No.: 1187182-65-5
• Molecular Formula: C₁₄H₁₂N₂O₃
• Molecular Weight: 256.261
• Mol file: 1187182-65-5.mol

Synonyms:3-(3-phenyl-1,2,4-oxadiazol-5-yl)propionic acid prop-2-ynyl ester

Chemical Property of 3-(3-phenyl-1,2,4-oxadiazol-5-yl)propionic acid prop-2-ynyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(3-phenyl-1,2,4-oxadiazol-5-yl)propionic acid prop-2-ynyl ester

There total 1 articles about 3-(3-phenyl-1,2,4-oxadiazol-5-yl)propionic acid prop-2-ynyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-<(3-Phenyl)-1,2,4-oxadiazol-5-yl>propionic acid (24088-59-3) + propargyl alcohol (107-19-7) → 3-(3-phenyl-1,2,4-oxadiazol-5-yl)propionic acid prop-2-ynyl ester (1187182-65-5)

Guidance literature:

3-<(3-Phenyl)-1,2,4-oxadiazol-5-yl>propionic acid; propargyl alcohol; With sulfuric acid; at 60 ℃; for 12h;

With sodium hydrogencarbonate; In ethyl acetate; Saturated solution;

DOI:10.1016/j.ejmech.2009.03.002

Reference yield: 83.0%

3-(3-phenyl-1,2,4-oxadiazol-5-yl)propionic acid prop-2-ynyl ester (1187182-65-5) + 1-azido-1-deoxy-β-D-glucopyranoside tetraacetate (13992-25-1) → O-{[1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1H-1,2,3-triazol-4-yl]methyl}-3-[3-phenyl-1,2,4-oxadiazol-5-yl]propanoate (1187182-79-1)

Guidance literature:

With copper diacetate; sodium L-ascorbate; In dichloromethane; water; at 20 ℃; for 20h;

DOI:10.1016/j.ejmech.2009.03.002

upstream raw materials:

3-<(3-Phenyl)-1,2,4-oxadiazol-5-yl>propionic acid

propargyl alcohol

Downstream raw materials:

O-{[1-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1H-1,2,3-triazol-4-yl]methyl}-3-[3-phenyl-1,2,4-oxadiazol-5-yl]propanoate