Technology Process of 1-amino-2,3,4,6-tetra-O-benzyl-1-deoxy-D-glucopyranose
There total 4 articles about 1-amino-2,3,4,6-tetra-O-benzyl-1-deoxy-D-glucopyranose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 78 percent / NaN3 / hexamethylphosphoric acid triamide / 4 h / 20 °C
2.1: 86 percent / NaOMe / methanol / 2 h / 20 °C
3.1: NaH / dimethylsulfoxide / 1 h / 20 °C
3.2: 73 percent / dimethylsulfoxide / 3 h / 20 °C
4.1: H2; Et3N / Lindlar's catalyst / tetrahydrofuran; methanol / 16 h / 1520 Torr
With
sodium azide; hydrogen; sodium methylate; sodium hydride; triethylamine;
Lindlar's catalyst;
In
tetrahydrofuran; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; dimethyl sulfoxide;
1.1: Substitution / 2.1: Substitution / 3.1: Metallation / 3.2: Etherification / 4.1: Catalytic hydrogenation;
DOI:10.1515/znb-1999-0519
- Guidance literature:
-
With
hydrogen; triethylamine;
Lindlar's catalyst;
In
tetrahydrofuran; methanol;
for 16h;
under 1520 Torr;
DOI:10.1515/znb-1999-0519
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: NaH / dimethylsulfoxide / 1 h / 20 °C
1.2: 73 percent / dimethylsulfoxide / 3 h / 20 °C
2.1: H2; Et3N / Lindlar's catalyst / tetrahydrofuran; methanol / 16 h / 1520 Torr
With
hydrogen; sodium hydride; triethylamine;
Lindlar's catalyst;
In
tetrahydrofuran; methanol; dimethyl sulfoxide;
1.1: Metallation / 1.2: Etherification / 2.1: Catalytic hydrogenation;
DOI:10.1515/znb-1999-0519
