5E-6-(3-(2-benzoyl-3-cyclopropyl-guanidino)phenyl)-6-(3-pyridyl)hex-5-enoic acid

Base Information

Chemical Name:5E-6-(3-(2-benzoyl-3-cyclopropyl-guanidino)phenyl)-6-(3-pyridyl)hex-5-enoic acid
CAS No.:150760-23-9
Molecular Formula:C₃₀H₃₂N₄O₃
Molecular Weight:496.609
Hs Code.:

Synonyms:5E-6-(3-(2-benzoyl-3-cyclopropyl-guanidino)phenyl)-6-(3-pyridyl)hex-5-enoic acid

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Chemical Property of 5E-6-(3-(2-benzoyl-3-cyclopropyl-guanidino)phenyl)-6-(3-pyridyl)hex-5-enoic acid

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Technology Process of 5E-6-(3-(2-benzoyl-3-cyclopropyl-guanidino)phenyl)-6-(3-pyridyl)hex-5-enoic acid

There total 4 articles about 5E-6-(3-(2-benzoyl-3-cyclopropyl-guanidino)phenyl)-6-(3-pyridyl)hex-5-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6-[3-(N'-benzoyl-N''-cyclopentyl-guanidino)-phenyl]-6-pyridin-3-yl-hex-5-enoic acid methyl ester

: 150760-23-9
5E-6-(3-(2-benzoyl-3-cyclopropyl-guanidino)phenyl)-6-(3-pyridyl)hex-5-enoic acid

Guidance literature:: With sodium hydroxide; In isopropyl alcohol; at 25 ℃; for 4h; Yield given;
DOI:10.1021/jm9707941

Reference yield:

: 81282-38-4
N-diphenoxymethylene benzamide

: 150760-23-9
5E-6-(3-(2-benzoyl-3-cyclopropyl-guanidino)phenyl)-6-(3-pyridyl)hex-5-enoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / propan-2-ol / 4 h / 20 °C

2: propan-2-ol / 0.5 h / Heating

3: 2 M aq. NaOH / propan-2-ol / 4 h / 25 °C

With sodium hydroxide; In isopropyl alcohol;
DOI:10.1021/jm9707941

Reference yield:

: 149980-31-4
(E)-methyl 6-(3-aminophenyl)-6-(3-pyridyl)hex-5-enoate

: 150760-23-9
5E-6-(3-(2-benzoyl-3-cyclopropyl-guanidino)phenyl)-6-(3-pyridyl)hex-5-enoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / propan-2-ol / 4 h / 20 °C

2: propan-2-ol / 0.5 h / Heating

3: 2 M aq. NaOH / propan-2-ol / 4 h / 25 °C

With sodium hydroxide; In isopropyl alcohol;
DOI:10.1021/jm9707941