1-isopropyl-3,5-dimethyl-2-phenyl-1,2-dihydro-1,2-λ³-azaphosphinine

Base Information

• Chemical Name: 1-isopropyl-3,5-dimethyl-2-phenyl-1,2-dihydro-1,2-λ³-azaphosphinine
• CAS No.: 111077-78-2
• Molecular Formula: C₁₅H₂₀NP
• Molecular Weight: 245.304
• Mol file: 111077-78-2.mol

Synonyms:1-isopropyl-3,5-dimethyl-2-phenyl-1,2-dihydro-1,2-λ³-azaphosphinine

Chemical Property of 1-isopropyl-3,5-dimethyl-2-phenyl-1,2-dihydro-1,2-λ³-azaphosphinine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-isopropyl-3,5-dimethyl-2-phenyl-1,2-dihydro-1,2-λ³-azaphosphinine

There total 3 articles about 1-isopropyl-3,5-dimethyl-2-phenyl-1,2-dihydro-1,2-λ³-azaphosphinine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

propionaldehyde isopropylimine (28916-23-6) + Dichlorophenylphosphine (644-97-3) → 1-isopropyl-3,5-dimethyl-2-phenyl-1,2-dihydro-1,2-λ3-azaphosphinine (111077-78-2) + 1-isopropyl-3-ethyl-4-methyl-2-phenyl-2-oxo-1,2,4-azaphospholene (111077-81-7)

Guidance literature:

In benzene; for 5h; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1016/S0040-4020(01)87861-3

Reference yield: 41.0%

C18H30ClN2P*ClH → 1-isopropyl-3,5-dimethyl-2-phenyl-1,2-dihydro-1,2-λ3-azaphosphinine (111077-78-2) + 1-isopropyl-3-ethyl-4-methyl-2-phenyl-2-oxo-1,2,4-azaphospholene (111077-81-7)

Guidance literature:

With methanol; triethylamine; In benzene; for 5h; Yields of byproduct given;

DOI:10.1016/S0040-4039(00)85048-0

Reference yield:

Dichlorophenylphosphine (644-97-3) → 1-isopropyl-3,5-dimethyl-2-phenyl-1,2-dihydro-1,2-λ3-azaphosphinine (111077-78-2)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / 5 h / 20 °C

2: 41 percent / NEt₃, MeOH / benzene / 5 h

With methanol; triethylamine; In benzene;

DOI:10.1016/S0040-4039(00)85048-0

upstream raw materials:

propionaldehyde isopropylimine

Dichlorophenylphosphine

Downstream raw materials:

1-isopropyl-3,5-dimethyl-2-phenyl-2-thioxo-1,2-dihydro-1,2-azaphosphinine

1-isopropyl-3,5-dimethyl-2-oxo-2-phenyl-1,2-dihydro-1,2-azaphosphinine