epi-chlamydocin

Base Information

• Chemical Name: epi-chlamydocin
• CAS No.: 88643-73-6
• Molecular Formula: C₂₈H₃₈N₄O₆
• Molecular Weight: 526.633
• Mol file: 88643-73-6.mol

Synonyms:epi-chlamydocin

Chemical Property of epi-chlamydocin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of epi-chlamydocin

There total 134 articles about epi-chlamydocin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Dihydrochlamydocin (52574-64-8,107982-60-5,107982-61-6,108146-59-4) → chlamydocin (88643-73-6,53342-16-8)

Guidance literature:

With dichloro-acetic acid; dicyclohexyl-carbodiimide; In dimethyl sulfoxide;

Reference yield: 78.0%

C28H40N4O5 → chlamydocin (88643-73-6,53342-16-8)

Guidance literature:

C₂₈H₄₀N₄O₅; With manganese(III) acetylacetonate; In tetrahydrofuran; at 0 ℃; for 2h;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at -25 ℃; for 48h; diastereoselective reaction;

DOI:10.1021/acs.orglett.9b03305

Reference yield: 68.0%

cyclo(-(D)-Pro-(L)-Phe-AIB-(L)-(2S,9R,10R)-2-amino-8-oxo-9,10-epoxy-10-trimethylsilyldecanoic acid-) → chlamydocin (88643-73-6,53342-16-8)

Guidance literature:

With tetrabutyl ammonium fluoride; In dimethyl sulfoxide; for 48h;

DOI:10.1016/S0040-4020(01)88010-8

upstream raw materials:

(5S,11S,13aR)-5-Benzyl-8,8-dimethyl-11-(6-oxo-oct-7-enyl)-decahydro-3a,6,9,12-tetraaza-cyclopentacyclododecene-4,7,10,13-tetraone

(5S,11S,13aR)-5-Benzyl-11-(6-hydroxy-6-oxiranyl-hexyl)-8,8-dimethyl-decahydro-3a,6,9,12-tetraaza-cyclopentacyclododecene-4,7,10,13-tetraone

Dihydrochlamydocin

8-Benzyloxy-6(S),7(S)-O-isopropylidene-1-octanal