<4-(4-Oxo-2-phenyl-3(4H)-quinazolinyl)-phenoxy>acetic acid (1,2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazide

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Chemical Name:<4-(4-Oxo-2-phenyl-3(4H)-quinazolinyl)-phenoxy>acetic acid (1,2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazide
CAS No.:106077-33-2
Molecular Formula:C₃₀H₂₁N₅O₄
Molecular Weight:515.528
Hs Code.:

Synonyms:<4-(4-Oxo-2-phenyl-3(4H)-quinazolinyl)-phenoxy>acetic acid (1,2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazide

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Chemical Property of <4-(4-Oxo-2-phenyl-3(4H)-quinazolinyl)-phenoxy>acetic acid (1,2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazide

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Technology Process of <4-(4-Oxo-2-phenyl-3(4H)-quinazolinyl)-phenoxy>acetic acid (1,2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazide

There total 3 articles about <4-(4-Oxo-2-phenyl-3(4H)-quinazolinyl)-phenoxy>acetic acid (1,2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 91-56-5,1186480-61-4,84788-92-1
indole-2,3-dione

: 106077-13-8
<4-(4-Oxo-2-phenyl-3(4H)-quinazolinyl)phenoxy>acetic acid hydrazide

: 106077-33-2
<4-(4-Oxo-2-phenyl-3(4H)-quinazolinyl)-phenoxy>acetic acid (1,2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazide

Guidance literature:: With acetic acid; In N,N-dimethyl-formamide; at 70 - 75 ℃; for 16h;
DOI:10.1515/HC.2008.14.1-2.107

Reference yield:

: 106077-12-7
Ethyl-<4-(4-oxo-2-phenyl-3(4H)-quinazolinyl)phenoxy>acetate

: 106077-33-2
<4-(4-Oxo-2-phenyl-3(4H)-quinazolinyl)-phenoxy>acetic acid (1,2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / 99percent N₂H₄*H₂O / ethanol / 12 h / Heating

2: 70 percent / glacial acetic acid / ethanol / 4 h / Heating

With hydrazine hydrate; acetic acid; In ethanol;

Reference yield:

: 37856-23-8
2-phenyl-3-(4-hydroxyphenyl)-4-oxo(3H)-quinazoline

: 106077-33-2
<4-(4-Oxo-2-phenyl-3(4H)-quinazolinyl)-phenoxy>acetic acid (1,2-dihydro-2-oxo-3H-indol-3-ylidene) hydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / K₂CO₃ / acetone / 48 h / Heating

2: 70 percent / 99percent N₂H₄*H₂O / ethanol / 12 h / Heating

3: 70 percent / glacial acetic acid / ethanol / 4 h / Heating

With potassium carbonate; hydrazine hydrate; acetic acid; In ethanol; acetone;