C₂₃H₃₄N₂O₈

Base Information

• Chemical Name: C₂₃H₃₄N₂O₈
• CAS No.: 1407508-17-1
• Molecular Formula: C₂₃H₃₄N₂O₈
• Molecular Weight: 466.532
• Mol file: 1407508-17-1.mol

Synonyms:C₂₃H₃₄N₂O₈

Chemical Property of C₂₃H₃₄N₂O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₃₄N₂O₈

There total 8 articles about C₂₃H₃₄N₂O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C29H48N2O8Si (1407508-16-0) → C23H34N2O8 (1407508-17-1)

Guidance literature:

C₂₉H₄₈N₂O₈Si; With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

With water; In tetrahydrofuran;

DOI:10.1016/j.tetasy.2012.08.008

Reference yield:

(2S,3S,5R,6R)-3-tert-butyldimethylsilyloxymethyl-2-hydroxymethyl-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane (241811-68-7) → C23H34N2O8 (1407508-17-1)

Guidance literature:

Multi-step reaction with 5 steps

1: dmap; pyridine / 0 - 20 °C / Inert atmosphere

2: sodium azide / N,N-dimethyl-formamide / 18 h / 70 °C / Inert atmosphere

3: hydrogen; 10% Pd/C / ethyl acetate; ethanol / 3 h / 2585.81 Torr

4: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; benzotriazol-1-ol / dichloromethane / 0 - 20 °C / Inert atmosphere

5: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

With pyridine; dmap; sodium azide; 10% Pd/C; tetrabutyl ammonium fluoride; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; ethanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1016/j.tetasy.2012.08.008

Reference yield:

(2S,3S,5R,6R)-3-(tert-butyldimethylsilyloxymethyl)-2-(p-toluenesulfonyloxymethyl)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane (1407508-13-7) → C23H34N2O8 (1407508-17-1)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium azide / N,N-dimethyl-formamide / 18 h / 70 °C / Inert atmosphere

2: hydrogen; 10% Pd/C / ethyl acetate; ethanol / 3 h / 2585.81 Torr

3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; benzotriazol-1-ol / dichloromethane / 0 - 20 °C / Inert atmosphere

4: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

With sodium azide; 10% Pd/C; tetrabutyl ammonium fluoride; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; ethanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1016/j.tetasy.2012.08.008

upstream raw materials:

(2S,3S,5R,6R)-3-(tert-butyldimethylsilyloxymethyl)-2-(p-toluenesulfonyloxymethyl)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane

(2R,3R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane-2,3-dicarbothioic acid di-S-ethyl ester

(2S,3S,5R,6R)-3-(tert-butyldimethylsilyloxymethyl)-2-azidomethyl-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane

(2S,3S,5R,6R)-3-(tert-butyldimethylsilyloxymethyl)-2-aminomethyl-5,6-dimethoxy-5,6-dimethyl-1,4-dioxane

Downstream raw materials:

C₂₃H₃₂N₂O₉