(Z)-(2R,3R,4S,8S,9R,10S)-3,9-bis-(tert-butyldimethylsilanyloxy)-11-(4-methoxybenzyloxy)-2,4,6,8,10-pentamethyl-undec-6-en-1-ol

Base Information

• Chemical Name: (Z)-(2R,3R,4S,8S,9R,10S)-3,9-bis-(tert-butyldimethylsilanyloxy)-11-(4-methoxybenzyloxy)-2,4,6,8,10-pentamethyl-undec-6-en-1-ol
• CAS No.: 1184762-11-5
• Molecular Formula: C₃₆H₆₈O₅Si₂
• Molecular Weight: 637.104
• Mol file: 1184762-11-5.mol

Synonyms:(Z)-(2R,3R,4S,8S,9R,10S)-3,9-bis-(tert-butyldimethylsilanyloxy)-11-(4-methoxybenzyloxy)-2,4,6,8,10-pentamethyl-undec-6-en-1-ol

Chemical Property of (Z)-(2R,3R,4S,8S,9R,10S)-3,9-bis-(tert-butyldimethylsilanyloxy)-11-(4-methoxybenzyloxy)-2,4,6,8,10-pentamethyl-undec-6-en-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-(2R,3R,4S,8S,9R,10S)-3,9-bis-(tert-butyldimethylsilanyloxy)-11-(4-methoxybenzyloxy)-2,4,6,8,10-pentamethyl-undec-6-en-1-ol

There total 1 articles about (Z)-(2R,3R,4S,8S,9R,10S)-3,9-bis-(tert-butyldimethylsilanyloxy)-11-(4-methoxybenzyloxy)-2,4,6,8,10-pentamethyl-undec-6-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

(S)-4-benzyl-3-[(Z)-(2S,3R,4S,8S,9R,10S)-3,9-bis-(tert-butyldimethylsilanyloxy)-11-(4-methoxybenzyloxy)-2,4,6,8,10-pentamethylundec-6-enoyl]oxazolidin-2-one (1184762-63-7) → (Z)-(2R,3R,4S,8S,9R,10S)-3,9-bis-(tert-butyldimethylsilanyloxy)-11-(4-methoxybenzyloxy)-2,4,6,8,10-pentamethyl-undec-6-en-1-ol (1184762-11-5)

Guidance literature:

With lithium borohydride; In tetrahydrofuran; methanol; diethyl ether; at 0 ℃; for 1.5h;

DOI:10.1002/anie.200901740

Reference yield:

(Z)-(2R,3R,4S,8S,9R,10S)-3,9-bis-(tert-butyldimethylsilanyloxy)-11-(4-methoxybenzyloxy)-2,4,6,8,10-pentamethyl-undec-6-en-1-ol (1184762-11-5) → C36H66O5Si2

Guidance literature:

With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1002/anie.200901740

upstream raw materials:

(S)-4-benzyl-3-[(Z)-(2S,3R,4S,8S,9R,10S)-3,9-bis-(tert-butyldimethylsilanyloxy)-11-(4-methoxybenzyloxy)-2,4,6,8,10-pentamethylundec-6-enoyl]oxazolidin-2-one