[3-Fluoro-4-(morpholin-4-yl)phenyl]methanamine

Base Information

Chemical Name:[3-Fluoro-4-(morpholin-4-yl)phenyl]methanamine
CAS No.:870843-45-1
Molecular Formula:C₁₁H₁₅FN₂O
Molecular Weight:210.251
Hs Code.:
European Community (EC) Number:860-874-1
ChEMBL ID:CHEMBL4533987

Synonyms:[3-fluoro-4-(morpholin-4-yl)phenyl]methanamine;870843-45-1;(3-Fluoro-4-morpholinophenyl)methanamine;(3-fluoro-4-morpholin-4-ylphenyl)methanamine;SCHEMBL1239414;CHEMBL4533987;GULVUKFJQUDLSH-UHFFFAOYSA-N;AKOS008118509;3-fluoro-4-(morpholin-4-yl)benzylamine;CS-0106547;EN300-45192;D76648;Z362596512

Suppliers and Price of [3-Fluoro-4-(morpholin-4-yl)phenyl]methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of [3-Fluoro-4-(morpholin-4-yl)phenyl]methanamine

Chemical Property:

XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:210.11684127
Heavy Atom Count:15
Complexity:197

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1C2=C(C=C(C=C2)CN)F

Technology Process of [3-Fluoro-4-(morpholin-4-yl)phenyl]methanamine

There total 2 articles about [3-Fluoro-4-(morpholin-4-yl)phenyl]methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 588708-64-9
3-fluoro-4-(morpholin-4-yl)benzonitrile

: 870843-45-1
3-fluoro-4-morpholin-4-yl-benzylamine

Guidance literature:: With sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1002/cmdc.201700307

Reference yield:

: 64248-62-0
3,4-Difluorobenzonitrile

: 870843-45-1
3-fluoro-4-morpholin-4-yl-benzylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / K₂CO₃ / dimethylsulfoxide / 8 h / 90 °C

2: Red-Al / tetrahydrofuran; toluene / 3 h / 20 °C

With potassium carbonate; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; dimethyl sulfoxide; toluene;
DOI:10.1021/jm050765n