11α-benzyloxy-14α-hydroxy-3-O-methylestradiol-17β

Base Information

Chemical Name:11α-benzyloxy-14α-hydroxy-3-O-methylestradiol-17β
CAS No.:76555-89-0
Molecular Formula:C₂₆H₃₂O₄
Molecular Weight:408.538
Hs Code.:

Synonyms:11α-benzyloxy-14α-hydroxy-3-O-methylestradiol-17β

Suppliers and Price of 11α-benzyloxy-14α-hydroxy-3-O-methylestradiol-17β

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 11α-benzyloxy-14α-hydroxy-3-O-methylestradiol-17β

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 11α-benzyloxy-14α-hydroxy-3-O-methylestradiol-17β

There total 7 articles about 11α-benzyloxy-14α-hydroxy-3-O-methylestradiol-17β which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.9%

: 76555-90-3
11-benzyloxy-14α-hydroxy-3-methoxyestra-1,3,5(10)-trien-17-one

: 76555-89-0
11α-benzyloxy-14α-hydroxy-3-O-methylestradiol-17β

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 ℃;
DOI:10.1039/P19800002793

Reference yield:

: 70833-75-9
7-[1-hydroxy-2-(6-methyl-1,4,8,11-tetraoxa-dispiro[4.1.4.2]tridec-6-yl)-ethyl]-3-methoxy-bicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile

: 76555-89-0
11α-benzyloxy-14α-hydroxy-3-O-methylestradiol-17β

Guidance literature:: Multi-step reaction with 6 steps

1: 81.2 percent / NaH, liquid NH₃, Na / tetrahydrofuran / 1.) room temperature, 30 min, 2.) - 78 deg C, 3 h

2: 92.1 percent / NaH / tetrahydrofuran / 5 h / 60 °C

3: 97.7 percent / 10percent HCl / tetrahydrofuran / 5 h / Ambient temperature

4: 46.6 percent / tetrahydrofuran / 4 h / Ambient temperature

5: 37 percent / various solvent(s) / 6 h / 180 °C

6: 74.9 percent / NaBH₄ / methanol / 0 °C

With hydrogenchloride; sodium tetrahydroborate; ammonia; sodium; sodium hydride; In tetrahydrofuran; methanol;
DOI:10.1039/P19800002793

Reference yield:

: 76555-94-7
1,1:3,3-bisethylenedioxy-2-<2-hydroxy-2-(4-methoxy-1,2-dihydrobenzocyclobuten-1-yl)ethyl>-2-methylcyclopentane

: 76555-89-0
11α-benzyloxy-14α-hydroxy-3-O-methylestradiol-17β

Guidance literature:: Multi-step reaction with 5 steps

1: 92.1 percent / NaH / tetrahydrofuran / 5 h / 60 °C

2: 97.7 percent / 10percent HCl / tetrahydrofuran / 5 h / Ambient temperature

3: 46.6 percent / tetrahydrofuran / 4 h / Ambient temperature

4: 37 percent / various solvent(s) / 6 h / 180 °C

5: 74.9 percent / NaBH₄ / methanol / 0 °C

With hydrogenchloride; sodium tetrahydroborate; sodium hydride; In tetrahydrofuran; methanol;
DOI:10.1039/P19800002793