2-(Fluoromethoxy)benzaldehyde

Base Information

Chemical Name:2-(Fluoromethoxy)benzaldehyde
CAS No.:221013-25-8
Molecular Formula:C₈H₇FO₂
Molecular Weight:154.141
Hs Code.:
DSSTox Substance ID:DTXSID50602013
Nikkaji Number:J1.038.086C
Wikidata:Q82498924
Mol file:221013-25-8.mol

Synonyms:221013-25-8;2-(Fluoromethoxy)benzaldehyde;2-fluoromethoxybenzaldehyde;Fluormethoxybenzaldehyd;SCHEMBL834422;DTXSID50602013;NVSAAKRWQJRUKN-UHFFFAOYSA-N;BENZALDEHYDE, 2-(FLUOROMETHOXY)-;Benzaldehyde, 2-(fluoromethoxy)- (9CI);DB-273523

Suppliers and Price of 2-(Fluoromethoxy)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 2-(Fluoromethoxy)benzaldehyde

Chemical Property:

PSA：26.30000
LogP:1.80490
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:154.04300762
Heavy Atom Count:11
Complexity:127

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C=O)OCF

Technology Process of 2-(Fluoromethoxy)benzaldehyde

There total 3 articles about 2-(Fluoromethoxy)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 221013-11-2
2-chloromethoxybenzaldehyde

: 221013-25-8
2-fluoromethoxybenzaldehyde

Guidance literature:: With tetrabutyl ammonium fluoride; In dichloromethane; for 20h; Ambient temperature;
DOI:10.3891/acta.chem.scand.53-0041

Reference yield:

: 128455-69-6
2-(methylthio)methoxybenzaldehyde

: 221013-25-8
2-fluoromethoxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / sulfuryl chloride / CH₂Cl₂ / 0.17 h / 0 °C

2: 47 percent / tetrabutylammmonium fluoride / CH₂Cl₂ / 20 h / Ambient temperature

With sulfuryl dichloride; tetrabutyl ammonium fluoride; In dichloromethane;
DOI:10.3891/acta.chem.scand.53-0041

Reference yield:

: 90-02-8
salicylaldehyde

: 221013-25-8
2-fluoromethoxybenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 25 percent / sodium hydride, sodium iodide / dimethylformamide / 12 h / 0 - 20 °C

2: 96 percent / sulfuryl chloride / CH₂Cl₂ / 0.17 h / 0 °C

3: 47 percent / tetrabutylammmonium fluoride / CH₂Cl₂ / 20 h / Ambient temperature

With sulfuryl dichloride; tetrabutyl ammonium fluoride; sodium hydride; sodium iodide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.3891/acta.chem.scand.53-0041