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Technology Process of Antalarmin hydrochloride

Antalarmin hydrochloride

Base Information
  • Chemical Name:Antalarmin hydrochloride
  • CAS No.:220953-69-5
  • Molecular Formula:C24H34 N4 . Cl H
  • Molecular Weight:415.01
  • Hs Code.:
  • DSSTox Substance ID:DTXSID00582018
  • Mol file:220953-69-5.mol
Antalarmin hydrochloride

Synonyms:Antalarmin hydrochloride;220953-69-5;Antalarmin (Hydrochloride);N-butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine;hydrochloride;N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride;SCHEMBL25395568;DTXSID00582018;CGDGXEDXEXACKQ-UHFFFAOYSA-N;EX-A6937;VIA95369;MFCD05664721;AKOS024457290;MS-27191;N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolol[2,3-d]pyrimidin-4-amine hydrochloride;HY-103377;CS-0027773;E98747;Antalarmin hydrochloride, >=98% (HPLC), solid;J-014490;N-Butyl-N-ethyl-7-mesityl-2,5,6-trimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride;Butyl-ethyl-[2,5,6-trimethyl-7-(2,4,6-trimethyl-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-amine hydrochloride;N-Butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine--hydrogen chloride (1/1)

Suppliers and Price of Antalarmin hydrochloride
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Antalarmin hydrochloride
  • 25mg
  • $ 265.00
  • Tocris
  • Antalarmin hydrochloride ≥99%(HPLC)
  • 10
  • $ 216.00
  • Tocris
  • Antalarmin hydrochloride ≥99%(HPLC)
  • 50
  • $ 876.00
  • Sigma-Aldrich
  • Antalarmin hydrochloride ≥98% (HPLC), solid
  • 50mg
  • $ 774.00
  • Sigma-Aldrich
  • Antalarmin hydrochloride ≥98% (HPLC), solid
  • 10mg
  • $ 225.00
  • Cayman Chemical
  • Antalarmin (hydrochloride) ≥98%
  • 25mg
  • $ 267.00
  • Cayman Chemical
  • Antalarmin (hydrochloride) ≥98%
  • 50mg
  • $ 445.00
  • Cayman Chemical
  • Antalarmin (hydrochloride) ≥98%
  • 10mg
  • $ 125.00
  • Cayman Chemical
  • Antalarmin (hydrochloride) ≥98%
  • 5mg
  • $ 89.00
  • ApexBio Technology
  • Antalarmin hydrochloride
  • 10mg
  • $ 263.00
Total 57 raw suppliers
Chemical Property of Antalarmin hydrochloride
Chemical Property:
  • PSA：33.95000 
  • LogP:6.69930 
  • Storage Temp.:2-8°C 
  • Solubility.:DMSO: ~24 mg/mL, soluble 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:6
  • Exact Mass:414.2550248
  • Heavy Atom Count:29
  • Complexity:485
Purity/Quality:

99%, *data from raw suppliers

Antalarmin hydrochloride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
  • Safety Statements: 22-24/25 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:CCCCN(CC)C1=NC(=NC2=C1C(=C(N2C3=C(C=C(C=C3C)C)C)C)C)C.Cl
  • Description Corticotropin-releasing hormone (CRH) secreted from the hypothalamus is the major regulator of pituitary corticotropin-release and consequent glucocorticoid secretion. Antalarmin is a selective, nonpeptide antagonist of the CRH receptor 1 (Ki = 1 nM) that, consequently, reduces the release of corticotropin in response to chronic stress. Through its antagonism of central CRH signaling, antalarmin can reduce endocrinological, cardiovascular, and behavioral responses to stressful stimuli. It has also been shown to reduce dose escalation in cocaine-addicted rats, to produce anti-inflammatory effects in arthritis models, and to suppress stress-induced gastric ulceration related to irritable bowel syndrome.
  • Uses Antalarmin hydrochloride is a non-peptide CRF1 corticotropin-releasing factor receptor antagonist.
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