3-[(4-amino-3-carboxyphenyl)carbonyl]imidazo[1,5-a]pyridine-6-carboxylic acid

Base Information

Chemical Name:3-[(4-amino-3-carboxyphenyl)carbonyl]imidazo[1,5-a]pyridine-6-carboxylic acid
CAS No.:1354904-60-1
Molecular Formula:C₁₆H₁₁N₃O₅
Molecular Weight:325.28
Hs Code.:

Synonyms:3-[(4-amino-3-carboxyphenyl)carbonyl]imidazo[1,5-a]pyridine-6-carboxylic acid

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Chemical Property of 3-[(4-amino-3-carboxyphenyl)carbonyl]imidazo[1,5-a]pyridine-6-carboxylic acid

Chemical Property:

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Technology Process of 3-[(4-amino-3-carboxyphenyl)carbonyl]imidazo[1,5-a]pyridine-6-carboxylic acid

There total 4 articles about 3-[(4-amino-3-carboxyphenyl)carbonyl]imidazo[1,5-a]pyridine-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 944445-57-2
4-oxo-2-phenyl-4H-3,1-benzoxazine-6-carbonyl chloride

: 139183-89-4
methyl imidazo[1,5-a] pyridine-6-carboxylate

: 1354904-60-1
3-[(4-amino-3-carboxyphenyl)carbonyl]imidazo[1,5-a]pyridine-6-carboxylic acid

Guidance literature:: 4-oxo-2-phenyl-4H-3,1-benzoxazine-6-carbonyl chloride; methyl imidazo[1,5-a] pyridine-6-carboxylate; With triethylamine; In 1,2-dichloro-ethane; at 20 ℃; for 24h; Inert atmosphere;

With water; potassium hydroxide; In 1-methyl-pyrrolidin-2-one; at 100 ℃; for 8h;

Reference yield:

: C₂₄H₁₅N₃O₅

: 1354904-60-1
3-[(4-amino-3-carboxyphenyl)carbonyl]imidazo[1,5-a]pyridine-6-carboxylic acid

Guidance literature:: C₂₄H₁₅N₃O₅; With water; potassium hydroxide; In 1-methyl-pyrrolidin-2-one; at 100 ℃; for 4h;

With hydrogenchloride; In 1-methyl-pyrrolidin-2-one; water;

Reference yield:

: 139183-89-4
methyl imidazo[1,5-a] pyridine-6-carboxylate

: 1354904-60-1
3-[(4-amino-3-carboxyphenyl)carbonyl]imidazo[1,5-a]pyridine-6-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / 1,2-dichloro-ethane / 24 h / 20 °C / Inert atmosphere

2: potassium hydroxide; water / 1-methyl-pyrrolidin-2-one / 4 h / 100 °C

With water; triethylamine; potassium hydroxide; In 1-methyl-pyrrolidin-2-one; 1,2-dichloro-ethane;