2-[4-(((3,4,5-trichlorobenzoyl)-amino)methyl)phenoxy]-2-methyl propionic acid

Base Information

Chemical Name:2-[4-(((3,4,5-trichlorobenzoyl)-amino)methyl)phenoxy]-2-methyl propionic acid
CAS No.:131179-85-6
Molecular Formula:C₁₈H₁₆Cl₃NO₄
Molecular Weight:416.688
Hs Code.:

Synonyms:2-[4-(((3,4,5-trichlorobenzoyl)-amino)methyl)phenoxy]-2-methyl propionic acid

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Chemical Property of 2-[4-(((3,4,5-trichlorobenzoyl)-amino)methyl)phenoxy]-2-methyl propionic acid

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Technology Process of 2-[4-(((3,4,5-trichlorobenzoyl)-amino)methyl)phenoxy]-2-methyl propionic acid

There total 3 articles about 2-[4-(((3,4,5-trichlorobenzoyl)-amino)methyl)phenoxy]-2-methyl propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 55458-79-2
2-<4-(aminomethyl)phenoxy>-2-methylpropionic acid

: 42221-50-1
3,4,5-trichloro-benzoyl chloride

: 131179-85-6
2-[4-(((3,4,5-trichlorobenzoyl)-amino)methyl)phenoxy]-2-methyl propionic acid

Guidance literature:: With sodium hydroxide; In water; for 1h; Ambient temperature;
DOI:10.1021/jm00106a041

Reference yield:

: 51-39-8
3,4,5-trichlorobenzoic acid

: 131179-85-6
2-[4-(((3,4,5-trichlorobenzoyl)-amino)methyl)phenoxy]-2-methyl propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 1 h / Heating

2: 59 percent / NaOH / H₂O / 1 h / Ambient temperature

With sodium hydroxide; thionyl chloride; In water;
DOI:10.1021/jm00106a041