Fmoc-Ala-OPfp ((9H-fluoren-9-yl-methoxy)carbonyl-L-alanine pentafluorophenyl ester)

Base Information

• Chemical Name: Fmoc-Ala-OPfp ((9H-fluoren-9-yl-methoxy)carbonyl-L-alanine pentafluorophenyl ester)
• CAS No.: 1310380-30-3
• Molecular Formula: C₄₁H₃₈N₂O₆
• Molecular Weight: 654.763

Synonyms:Fmoc-Ala-OPfp ((9H-fluoren-9-yl-methoxy)carbonyl-L-alanine pentafluorophenyl ester)

Chemical Property of Fmoc-Ala-OPfp ((9H-fluoren-9-yl-methoxy)carbonyl-L-alanine pentafluorophenyl ester)

Chemical Property:

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Technology Process of Fmoc-Ala-OPfp ((9H-fluoren-9-yl-methoxy)carbonyl-L-alanine pentafluorophenyl ester)

There total 1 articles about Fmoc-Ala-OPfp ((9H-fluoren-9-yl-methoxy)carbonyl-L-alanine pentafluorophenyl ester) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(2-phenyl-benzo[b]furan-3-yl)-prop-2-ynyl 4-amino-2,3,4,6-tetradeoxy-α-L-threo-hexopyranoside (1192234-92-6) + (9H-fluoren-9-yl-methoxy)carbonyl-L-alanine pentafluorophenyl ester (86060-86-8) → Fmoc-Ala-OPfp ((9H-fluoren-9-yl-methoxy)carbonyl-L-alanine pentafluorophenyl ester) (1310380-30-3)

Guidance literature:

In dichloromethane; at 20 ℃; for 8h;

DOI:10.1016/j.bmcl.2011.02.051

Reference yield:

Fmoc-Ala-OPfp ((9H-fluoren-9-yl-methoxy)carbonyl-L-alanine pentafluorophenyl ester) (1310380-30-3) → 3-(2-phenyl-benzo[b]furan-3-yl)-prop-2-ynyl 4-N-L-ala-2,3,4,6-tetradeoxy-α-L-threo-hexopyranoside (1310380-31-4)

Guidance literature:

With piperidine; In dichloromethane;

DOI:10.1016/j.bmcl.2011.02.051

upstream raw materials:

3-(2-phenyl-benzo[b]furan-3-yl)-prop-2-ynyl 4-amino-2,3,4,6-tetradeoxy-α-L-threo-hexopyranoside

(9H-fluoren-9-yl-methoxy)carbonyl-L-alanine pentafluorophenyl ester

Downstream raw materials:

3-(2-phenyl-benzo[b]furan-3-yl)-prop-2-ynyl 4-N-L-ala-2,3,4,6-tetradeoxy-α-L-threo-hexopyranoside

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