N-[2-[(phenylmethyl)sulfonyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine

Base Information

• Chemical Name: N-[2-[(phenylmethyl)sulfonyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine
• CAS No.: 1246034-66-1
• Molecular Formula: C₂₃H₂₄N₆O₂S₂
• Molecular Weight: 480.615

Synonyms:N-[2-[(phenylmethyl)sulfonyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine

Chemical Property of N-[2-[(phenylmethyl)sulfonyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-[(phenylmethyl)sulfonyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine

There total 1 articles about N-[2-[(phenylmethyl)sulfonyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[2-[(phenylmethyl)thio]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine (1246034-65-0) → N-[2-[(phenylmethyl)sulfinyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine (1246034-67-2) + N-[2-[(phenylmethyl)sulfonyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine (1246034-66-1)

Guidance literature:

N-[2-[(phenylmethyl)thio]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine; With Oxone; In N,N-dimethyl-formamide;

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; for 0.333333h;

Reference yield: 28.0%

4-(morpholin-4-yl)cyclohexan-1-amine (847798-79-2) + N-[2-[(phenylmethyl)sulfonyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine (1246034-66-1) → N2-[trans-4-(4-morpholinyl)cyclohexyl]-6-(1-piperidinylmethyl)-N4-[1,3]thiazolo[5,4-b]pyridin-2-yl-2,4-pyrimidinediamine

Guidance literature:

In isopropyl alcohol; at 160 ℃; for 0.75h; Biotage "Initiator" microwave;

Reference yield: 15.0%

N-[2-[(phenylmethyl)sulfonyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine (1246034-66-1) + 3-(4-aminophenyl)propionic acid (2393-17-1) → 3-(4-{[4-(1-piperidinylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)-2-pyrimidinyl]amino}phenyl)propanoic acid (1246033-16-8)

Guidance literature:

With hydrogenchloride; In water; acetonitrile; at 150 ℃; for 2h; Biotage "Initiator" microwave;

upstream raw materials:

N-[2-[(phenylmethyl)thio]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine

Downstream raw materials:

3-(4-{[4-(1-piperidinylmethyl)-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)-2-pyrimidinyl]amino}phenyl)propanoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1246034-66-1 N-[2-[(phenylmethyl)sulfonyl]-6-(1-piperidinylmethyl)-4-pyrimidinyl][1,3]thiazolo[5,4-b]pyridin-2-amine

Send

Send

Metric Ton KG G Pound L ML

Send

Send