C₂₀H₁₅F₂N₃O₂S

Base Information

Chemical Name:C₂₀H₁₅F₂N₃O₂S
CAS No.:1372148-89-4
Molecular Formula:C₂₀H₁₅F₂N₃O₂S
Molecular Weight:399.421
Hs Code.:

C<sub>20</sub>H<sub>15</sub>F<sub>2</sub>N<sub>3</sub>O<sub>2</sub>S

Synonyms:C₂₀H₁₅F₂N₃O₂S

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₀H₁₅F₂N₃O₂S

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Technology Process of C₂₀H₁₅F₂N₃O₂S

There total 4 articles about C₂₀H₁₅F₂N₃O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 16114-47-9
3,5-dimethylisoxazole-4-boronic acid

: 1372148-87-2
C₁₅H₉ClF₂N₂OS

: 1372148-89-4
C₂₀H₁₅F₂N₃O₂S

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine; In 1,4-dioxane; for 5h; Reflux;
DOI:10.1055/s-0031-1290079

Reference yield:

: 412018-50-9
1-(4,6-dichloropyridin-3-yl)ethan-1-one

: 1372148-89-4
C₂₀H₁₅F₂N₃O₂S

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -40 °C / Inert atmosphere

1.2: 1.5 h / -40 - 20 °C

1.3: 0.33 h / 5 - 20 °C

2.1: potassium phosphate / dimethyl sulfoxide / 0.5 h / 100 °C

3.1: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine / 1,4-dioxane / 5 h / Reflux

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; triethylamine; lithium diisopropyl amide; In tetrahydrofuran; 1,4-dioxane; dimethyl sulfoxide; 3.1: Suzuki-Miyaura coupling;
DOI:10.1055/s-0031-1290079

Reference yield:

: 1372148-86-1
C₁₅H₁₀Cl₂F₂N₂OS

: 1372148-89-4
C₂₀H₁₅F₂N₃O₂S

Guidance literature:: Multi-step reaction with 2 steps

1: potassium phosphate / dimethyl sulfoxide / 0.5 h / 100 °C

2: dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; triethylamine / 1,4-dioxane / 5 h / Reflux

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate; triethylamine; In 1,4-dioxane; dimethyl sulfoxide; 2: Suzuki-Miyaura coupling;
DOI:10.1055/s-0031-1290079