Technology Process of 4-methoxyphenyl 4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3)-2,4-di-O-benzoyl-α-L-rhamnopyranoside
There total 12 articles about 4-methoxyphenyl 4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranosyl-(1->3)-2,4-di-O-benzoyl-α-L-rhamnopyranoside which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium hydrogencarbonate; thiourea;
In
methanol; dichloromethane;
at 25 ℃;
for 1h;
DOI:10.1081/CAR-120020480
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 62.5 percent / BF3*Et2O / CH2Cl2 / 22 h
2: 69.5 percent / sodium methoxide / methanol / 3 h
3: 77.5 percent / p-toluenesulfonic acid; molecular sieves 3 Angstroem / acetonitrile
4: 83 percent / triethylamine / CH2Cl2 / 3 h
5: 54.9 percent / N-iodosuccinimide; trifluoromethanesulfonic acid; molecular sieves 4 Angstroem / CH2Cl2 / 0.75 h
6: 91 percent / thiourea; NaHCO3 / methanol; CH2Cl2 / 1 h / 25 °C
With
N-iodo-succinimide; trifluorormethanesulfonic acid; 3 A molecular sieve; 4 A molecular sieve; boron trifluoride diethyl etherate; sodium methylate; sodium hydrogencarbonate; toluene-4-sulfonic acid; triethylamine; thiourea;
In
methanol; dichloromethane; acetonitrile;
DOI:10.1081/CAR-120020480
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 73 percent / p-toluenesulfonic acid / dimethylformamide / 5 h / 20 °C
2.1: 92 percent / pyridine / 4 h / 20 °C
3.1: 83.5 percent / acetic acid / H2O / 2 h / 80 °C
4.1: (+/-) camphor-10-sulfonic acid / CH2Cl2 / 0.25 h
4.2: 2.68 g / acetic acid / H2O / 0.5 h / 20 °C
5.1: 54.9 percent / N-iodosuccinimide; trifluoromethanesulfonic acid; molecular sieves 4 Angstroem / CH2Cl2 / 0.75 h
6.1: 91 percent / thiourea; NaHCO3 / methanol; CH2Cl2 / 1 h / 25 °C
With
pyridine; N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; 10-camphorsufonic acid; sodium hydrogencarbonate; toluene-4-sulfonic acid; acetic acid; thiourea;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1081/CAR-120020480