ester ter-butylique de l'acide (acetoxy methyl)-3(<-acetyl>-amino)-7 β cepheme-3 carboxylique-4

Base Information

• Chemical Name: ester ter-butylique de l'acide (acetoxy methyl)-3(<-acetyl>-amino)-7 β cepheme-3 carboxylique-4
• CAS No.: 68672-76-4
• Molecular Formula: C₃₈H₃₇N₅O₇S₂
• Molecular Weight: 739.873
• Mol file: 68672-76-4.mol

Synonyms:ester ter-butylique de l'acide (acetoxy methyl)-3(<-acetyl>-amino)-7 β cepheme-3 carboxylique-4

Chemical Property of ester ter-butylique de l'acide (acetoxy methyl)-3(<-acetyl>-amino)-7 β cepheme-3 carboxylique-4

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ester ter-butylique de l'acide (acetoxy methyl)-3(<-acetyl>-amino)-7 β cepheme-3 carboxylique-4

There total 5 articles about ester ter-butylique de l'acide (acetoxy methyl)-3(<-acetyl>-amino)-7 β cepheme-3 carboxylique-4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(methoxy-1 methyl-1 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4 (71092-00-7) → ester ter-butylique de l'acide (acetoxy methyl)-3(<-acetyl>-amino)-7 β cepheme-3 carboxylique-4 (68672-76-4)

Guidance literature:

With hydrogenchloride; In water; acetone; for 3h; Ambient temperature;

Reference yield:

2-(2-triphenylmethylamino-4-thiazolyl)-2-[Z-(1-methoxy-1-methylethyl)oxyimino]acetic acid (68672-71-9) → ester ter-butylique de l'acide (acetoxy methyl)-3(<-acetyl>-amino)-7 β cepheme-3 carboxylique-4 (68672-76-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 44 percent / dicyclohexylcarbodiimide / CH₂Cl₂ / 2 h

2: 75 percent / 1 N HCl / acetone; H₂O / 3 h / Ambient temperature

With hydrogenchloride; dicyclohexyl-carbodiimide; In dichloromethane; water; acetone;

Reference yield:

7-Aminocephalosporanic acid t-butyl ester (6187-87-7) → ester ter-butylique de l'acide (acetoxy methyl)-3(<-acetyl>-amino)-7 β cepheme-3 carboxylique-4 (68672-76-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 44 percent / dicyclohexylcarbodiimide / CH₂Cl₂ / 2 h

2: 75 percent / 1 N HCl / acetone; H₂O / 3 h / Ambient temperature

With hydrogenchloride; dicyclohexyl-carbodiimide; In dichloromethane; water; acetone;

upstream raw materials:

ester de tert-butylique de l'acide (acetoxy methyl)-3(<<(methoxy-1 methyl-1 ethoxy)-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4

2-(2-triphenylmethylamino-4-thiazolyl)-2-[Z-(1-methoxy-1-methylethyl)oxyimino]acetic acid

7-Aminocephalosporanic acid t-butyl ester

(Z)-2-Hydroxyimino-2-(2-triphenylmethylaminothiazol-4-yl)-acetic acid

Downstream raw materials:

sel de diethylammonium de l'acide (acetoxy methyl)-3(<<<(dimethyl-1,1 ethoxy)-2 oxo-2 phenyl-1 ethoxy>-imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4

sel de diethylammonium de l'acide (acetoxy methyl)-3(<<<(dimethyl-1,1 ethoxy)-2 oxo-2 ethoxy>imino-2 Z (tritylamino-2 thiazolyl-4)-2>-acetyl>-amino)-7 β cepheme-3 carboxylique-4