4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methyl butyl)amino] benzoic acid

Base Information

Chemical Name:4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methyl butyl)amino] benzoic acid
CAS No.:1190424-40-8
Molecular Formula:C₃₀H₂₆N₄O₃
Molecular Weight:490.561
Hs Code.:

Synonyms:4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methyl butyl)amino] benzoic acid

Suppliers and Price of 4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methyl butyl)amino] benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methyl butyl)amino] benzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methyl butyl)amino] benzoic acid

There total 6 articles about 4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methyl butyl)amino] benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1190424-39-5
2-methylpropan-2-yl 4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methylbutyl)amino]benzoate

: 1190424-40-8
4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methyl butyl)amino] benzoic acid

Guidance literature:: With hydrogenchloride; water; In 1,4-dioxane; at 100 ℃; for 2h; microwave irradiation;

Reference yield:

: 52602-39-8
9H-carbazol-4-ol

: 1190424-40-8
4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methyl butyl)amino] benzoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: triethylamine / dichloromethane / 24 h / 20 °C / Inert atmosphere

2: caesium carbonate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / 1,4-dioxane; water / 4 h / Inert atmosphere; Reflux

3: caesium carbonate / palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 4.5 h / Inert atmosphere; Reflux

4: potassium carbonate / dimethyl sulfoxide / 1.33 h / 90 °C / microwave irradiation

5: hydrogenchloride; water / 1,4-dioxane / 2 h / 100 °C / microwave irradiation

With hydrogenchloride; water; potassium carbonate; caesium carbonate; triethylamine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; dichloromethane; water; dimethyl sulfoxide;

Reference yield:

: 889858-12-2
4-bromo-2-fluoro-benzoic acid tert-butyl ester

: 1190424-40-8
4-[4-(6-cyanopyridin-3-yl)-9H-carbazol-9-yl]-2-[(3-hydroxy-3-methyl butyl)amino] benzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate / palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 4.5 h / Inert atmosphere; Reflux

2: potassium carbonate / dimethyl sulfoxide / 1.33 h / 90 °C / microwave irradiation

3: hydrogenchloride; water / 1,4-dioxane / 2 h / 100 °C / microwave irradiation

With hydrogenchloride; water; potassium carbonate; caesium carbonate; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; dimethyl sulfoxide;