RuCl2[(S)-xylbinap][(S)-daipen]

Base Information

• Chemical Name: RuCl2[(S)-xylbinap][(S)-daipen]
• CAS No.: 220114-01-2
• Molecular Formula: C₇₁H₇₄Cl₂N₂O₂P₂Ru
• Molecular Weight: 1221.3
• European Community (EC) Number: 803-138-7
• Mol file: 220114-01-2.mol

Synonyms:RuCl2[(S)-xylbinap][(S)-daipen];220114-01-2;[1-[2-Bis(3,5-dimethylphenyl)phosphanylnaphthalen-1-yl]naphthalen-2-yl]-bis(3,5-dimethylphenyl)phosphane;(2S)-1,1-bis(4-methoxyphenyl)-3-methylbutane-1,2-diamine;dichlororuthenium;MFCD09753027;[RuCl2{(S)-xylbinap}{(S)-daipen}];T72095;J-014419;(1-{2-[bis(3,5-dimethylphenyl)phosphanyl]naphthalen-1-yl}naphthalen-2-yl)bis(3,5-dimethylphenyl)phosphane

Chemical Property of RuCl2[(S)-xylbinap][(S)-daipen]

Chemical Property:

• Melting Point: 210-212 °C (decomp)
• PSA: 97.68000
• LogP: 17.31260
• Storage Temp.: 2-8°C
• Sensitive.: air sensitive
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 13
• Exact Mass: 1220.364599
• Heavy Atom Count: 80
• Complexity: 1320

Purity/Quality:

98%,99%, ^*data from raw suppliers

RuCl2[(S)-xylbinap][(S)-daipen] ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1=CC(=CC(=C1)P(C2=C(C3=CC=CC=C3C=C2)C4=C(C=CC5=CC=CC=C54)P(C6=CC(=CC(=C6)C)C)C7=CC(=CC(=C7)C)C)C8=CC(=CC(=C8)C)C)C.CC(C)C(C(C1=CC=C(C=C1)OC)(C2=CC=C(C=C2)OC)N)N.Cl[Ru]Cl
• Isomeric SMILES: CC1=CC(=CC(=C1)P(C2=C(C3=CC=CC=C3C=C2)C4=C(C=CC5=CC=CC=C54)P(C6=CC(=CC(=C6)C)C)C7=CC(=CC(=C7)C)C)C8=CC(=CC(=C8)C)C)C.CC(C)[C@@H](C(C1=CC=C(C=C1)OC)(C2=CC=C(C=C2)OC)N)N.Cl[Ru]Cl
• Uses: Catalyst for:Preparation of cyclometalated ruthenium 1,1-dianisyl-2-isopropyl-1,2-ethylenediamine complexes via asymmetric hydrogenation of ketonesEnantioselective hydrogenation of an α-alkoxy substituted ketone with chiral ruthenium (phosphinoferrocenyl)oxazoline complexesNonclassical asymmeteric hydrogen transfer between alcohols and carbonyl compoundsAsymmetric hydrogenation of amino and heteroaromatic ketonesPharmacologically active substituted oxazolidinone used as NPC1L1 ligand for inhibition of cholesterol absorption

Technology Process of RuCl2[(S)-xylbinap][(S)-daipen]

There total 1 articles about RuCl2[(S)-xylbinap][(S)-daipen] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

R-DAIPEN (166764-19-8) + [RuCl(p-cymene)((R)-xylbinap)]Cl (1345887-44-6,1365247-39-7,942296-45-9,944451-24-5,944451-25-6) → trans-RuCl2[(R)-xylbinap][(R)-daipen] (220114-01-2,220114-32-9,294638-74-7)

Guidance literature:

In toluene; at 80 ℃; for 2h; Inert atmosphere;

Reference yield: 1.0%

trans-RuCl2((S)-2,2'-bis(di-3,5-xylylphosphino)-1,1'-binaphthyl)((S)-1,1-di(4-anisyl)-2-isopropyl-1,2-ethylenediamine) (220114-01-2) → XylBINAP

Guidance literature:

With diethylamine; NH₂C(C₆H₄OCH₃)2CH(CH(CH₃)2)NH₂; In methanol; heated under reflux for 3 h;

DOI:10.1021/ja202296w

upstream raw materials:

R-DAIPEN

[RuCl(p-cymene)((R)-xylbinap)]Cl