(3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester

Base Information

Chemical Name:(3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester
CAS No.:185522-71-8
Molecular Formula:C₂₆H₃₃NO₇
Molecular Weight:471.551
Hs Code.:

Synonyms:(3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester

Suppliers and Price of (3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester

There total 6 articles about (3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 71432-55-8
2-tert-butyl-1,3-diisopropylisourea

: 185522-70-7
(3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 3-ethyl ester

: 185522-71-8
(3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester

Guidance literature:: With copper(l) chloride; at 25 ℃; for 16h;
DOI:10.1016/0957-4166(96)00407-7

Reference yield:

: 90-96-0
bis(p-methoxyphenyl)methanone

: 185522-71-8
(3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: NH₂OH*HCl / ethanol / 3 h / 80 °C

2: borane-pyridine complex, HCl / ethanol / -5 °C

3: benzene / 0.5 h / Heating

4: 82 percent / toluene / 36 h / 25 °C

5: 95 percent / LiOH, H₂O₂ / H₂O / -15 - 0 °C

6: 87 percent / CuCl / 16 h / 25 °C

With hydrogenchloride; lithium hydroxide; borane pyridine; hydroxylamine hydrochloride; dihydrogen peroxide; copper(l) chloride; In ethanol; water; toluene; benzene;
DOI:10.1016/0957-4166(96)00407-7

Reference yield:

: 54150-63-9
4,4'-dimethoxybenzophenone oxime

: 185522-71-8
(3S,5S)-2-[Bis-(4-methoxy-phenyl)-methyl]-isoxazolidine-3,5-dicarboxylic acid 5-tert-butyl ester 3-ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: borane-pyridine complex, HCl / ethanol / -5 °C

2: benzene / 0.5 h / Heating

3: 82 percent / toluene / 36 h / 25 °C

4: 95 percent / LiOH, H₂O₂ / H₂O / -15 - 0 °C

5: 87 percent / CuCl / 16 h / 25 °C

With hydrogenchloride; lithium hydroxide; borane pyridine; dihydrogen peroxide; copper(l) chloride; In ethanol; water; toluene; benzene;
DOI:10.1016/0957-4166(96)00407-7