tetraisopropyl ((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(phosphonate)

Base Information

• Chemical Name: tetraisopropyl ((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(phosphonate)
• CAS No.: 1262966-32-4
• Molecular Formula: C₂₂H₃₆O₆P₂
• Molecular Weight: 458.472
• Mol file: 1262966-32-4.mol

Synonyms:tetraisopropyl ((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(phosphonate)

Chemical Property of tetraisopropyl ((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(phosphonate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tetraisopropyl ((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(phosphonate)

There total 4 articles about tetraisopropyl ((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(phosphonate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

terephthalaldehyde, (623-27-8) + diisopropoxychlorophosphonium trimethylsilylmethylide (119494-32-5) → tetraisopropyl ((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(phosphonate) (1262966-32-4)

Guidance literature:

In tetrahydrofuran; diethyl ether; at -20 - 24 ℃; for 25h; regioselective reaction;

DOI:10.1080/10426507.2015.1054932

Reference yield:

diisopropyl hydrogenphosphonate (1809-20-7) + 1,4-bis(2,2-dibromoethenyl)benzene (77295-67-1) → tetraisopropyl ((1E,1'Z)-1,4-phenylenebis(ethene-2,1-diyl))bis(phosphonate) + tetraisopropyl ((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(phosphonate) (1262966-32-4)

Guidance literature:

With potassium phosphate; copper(l) iodide; N,N`-dimethylethylenediamine; In toluene; at 120 ℃; optical yield given as %de; stereoselective reaction; Inert atmosphere;

DOI:10.1039/c0cc01617a

Reference yield:

diisopropyl [(trimethylsilyl)methyl]phosphonite → tetraisopropyl ((1E,1'E)-1,4-phenylenebis(ethene-2,1-diyl))bis(phosphonate) (1262966-32-4)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrachloromethane / diethyl ether / 3 h / -70 - 20 °C

2: diethyl ether; tetrahydrofuran / 25 h / -20 - 24 °C

With tetrachloromethane; In tetrahydrofuran; diethyl ether;

DOI:10.1080/10426507.2015.1054932

upstream raw materials:

diisopropyl hydrogenphosphonate

1,4-bis(2,2-dibromoethenyl)benzene

terephthalaldehyde,

diisopropoxychlorophosphonium trimethylsilylmethylide