N-methyl-1-phenethylamine

Base Information

• Chemical Name: N-methyl-1-phenethylamine
• CAS No.: 32512-24-6
• Molecular Formula: C₉H₁₃N
• Molecular Weight: 135.209
• Hs Code.: 2921490090
• Mol file: 32512-24-6.mol

Synonyms:Benzylamine,N,a-dimethyl- (8CI); (RS)-N,a-Dimethylbenzylamine; (?à)-N,a-Dimethylbenzenemethanamine; MAPEA;Methyl(1-phenylethyl)amine; N,a-Dimethylbenzenemethanamine; N,a-Dimethylbenzylamine; N-Methyl-1-phenylethylamine;N-Methyl-a-phenylethylamine

Chemical Property of N-methyl-1-phenethylamine

Chemical Property:

• Vapor Pressure: 0.976mmHg at 25°C
• Refractive Index: 1.505
• Boiling Point: 178.7°C at 760 mmHg
• PKA: 9.77±0.10(Predicted)
• Flash Point: 61.6°C
• PSA: 12.03000
• Density: 0.911g/cm³
• LogP: 2.35790
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

99% ^*data from raw suppliers

methyl(1-phenylethyl)amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-methyl-1-phenethylamine

There total 1 articles about N-methyl-1-phenethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-formyl-(-)-α-phenylethylamine (6948-01-2,19145-06-3,31502-34-8,42412-77-1) → (-)-Methyl-<1-phenyl-ethyl>-amin (5933-40-4,19131-99-8,32512-24-6,42882-26-8)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

Reference yield: 93.0%

L(-)-N-Methyl-N-(α-phenylethyl)-amin (5933-40-4,19131-99-8,32512-24-6,42882-26-8) + bis(hydroxymethyl)phenylphosphine (3127-08-0) → Methyl-[({[methyl-((S)-1-phenyl-ethyl)-amino]-methyl}-phenyl-phosphanyl)-methyl]-((S)-1-phenyl-ethyl)-amine (75263-12-6)

Guidance literature:

DOI:10.1016/S0040-4039(00)92795-3

Reference yield: 87.0%

ethylphosphanediyl-bis-methanol (5849-96-7) + D(+)-N-Methyl-N-(α-phenylethyl)-amin (5933-40-4,19131-99-8,32512-24-6,42882-26-8) → [(Ethyl-{[methyl-((R)-1-phenyl-ethyl)-amino]-methyl}-phosphanyl)-methyl]-methyl-((R)-1-phenyl-ethyl)-amine (75263-10-4)

Guidance literature:

DOI:10.1016/S0040-4039(00)92795-3

upstream raw materials:

N-formyl-(-)-α-phenylethylamine

Downstream raw materials:

(2-Diphenylphosphanyl-ethyl)-methyl-(1-phenyl-ethyl)-amine

[(E)-2-(Diphenyl-phosphinoyl)-vinyl]-methyl-(1-phenyl-ethyl)-amine

N-methyl-N-<(-)-α-phenylethyl>-o-methoxybenzamide

(2-Diphenylphosphanyl-ethyl)-methyl-(1-phenyl-ethyl)-amine

Refernces

• 1、 Solov'eva, L. D.,Dem'yanovich, V. M.,Potapov, V. M.. "STEREOCHEMICAL INVESTIGATIONS. LII. CHIRAL AMIDES OF o-HYDROXY- AND o-METHOXY-SUBSTITUTED BENZOIC ACIDS". . p. 1099 - 1105. Retrieved 2007/10/02.