Technology Process of C17H24O4
There total 5 articles about C17H24O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium osmate(VI) dihydrate; methanesulfonamide; water; potassium carbonate; 4-[(R)-[(2R,4R,5S)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]-1-[(R)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]phthalazine; potassium hexacyanoferrate(III) / tert-butyl alcohol / 22 h / 0 - 10 °C
2: lithium borohydride; water / tetrahydrofuran
3: sodium hydride; 1-[(2,4,6-triisopropylphenyl)sulfonyl]-1H-imidazole / tetrahydrofuran / 0 °C
4: tetrahydrofuran / 0 - 20 °C
5: tetrabutyl ammonium fluoride / tetrahydrofuran
With
potassium osmate(VI) dihydrate; lithium borohydride; methanesulfonamide; tetrabutyl ammonium fluoride; water; sodium hydride; potassium carbonate; 4-[(R)-[(2R,4R,5S)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]-1-[(R)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]phthalazine; potassium hexacyanoferrate(III); 1-[(2,4,6-triisopropylphenyl)sulfonyl]-1H-imidazole;
In
tetrahydrofuran; tert-butyl alcohol;
1: Sharpless dihydroxylation / 3: Fraser-Reid epoxidation;
DOI:10.1016/j.tetlet.2010.11.013
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydride; 1-[(2,4,6-triisopropylphenyl)sulfonyl]-1H-imidazole / tetrahydrofuran / 0 °C
2: tetrahydrofuran / 0 - 20 °C
3: tetrabutyl ammonium fluoride / tetrahydrofuran
With
tetrabutyl ammonium fluoride; sodium hydride; 1-[(2,4,6-triisopropylphenyl)sulfonyl]-1H-imidazole;
In
tetrahydrofuran;
1: Fraser-Reid epoxidation;
DOI:10.1016/j.tetlet.2010.11.013