diphenyl benzyloxycarbonylamino-(4-(tert-butyloxycarbonylaminomethyl)phenyl)methanephosphonate

Base Information

Chemical Name:diphenyl benzyloxycarbonylamino-(4-(tert-butyloxycarbonylaminomethyl)phenyl)methanephosphonate
CAS No.:695171-96-1
Molecular Formula:C₃₃H₃₅N₂O₇P
Molecular Weight:602.624
Hs Code.:

Synonyms:diphenyl benzyloxycarbonylamino-(4-(tert-butyloxycarbonylaminomethyl)phenyl)methanephosphonate

Suppliers and Price of diphenyl benzyloxycarbonylamino-(4-(tert-butyloxycarbonylaminomethyl)phenyl)methanephosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of diphenyl benzyloxycarbonylamino-(4-(tert-butyloxycarbonylaminomethyl)phenyl)methanephosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of diphenyl benzyloxycarbonylamino-(4-(tert-butyloxycarbonylaminomethyl)phenyl)methanephosphonate

There total 5 articles about diphenyl benzyloxycarbonylamino-(4-(tert-butyloxycarbonylaminomethyl)phenyl)methanephosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 101-02-0
triphenyl phosphite

: 621-84-1
O-benzyl carbamate

: 156866-52-3
tert-butyl N-(4-formylbenzyl)carbamate

: 695171-96-1
diphenyl benzyloxycarbonylamino-(4-(tert-butyloxycarbonylaminomethyl)phenyl)methanephosphonate

Guidance literature:: With copper(II) bis(trifluoromethanesulfonate); In methanol; at 20 ℃; for 4h;
DOI:10.1021/jm0499209

Reference yield:

: 56-91-7
p-aminomethylbenzoic acid

: 695171-96-1
diphenyl benzyloxycarbonylamino-(4-(tert-butyloxycarbonylaminomethyl)phenyl)methanephosphonate

Guidance literature:: Multi-step reaction with 4 steps

1: aq. NaOH / dioxane / 20 °C

2: 86 percent / LiAlH₄ / dioxane; tetrahydrofuran

3: 79 percent / Dess-Martin periodane / CH₂Cl₂ / 3 h / 20 °C

4: 39 percent / Cu(OTf)2 / methanol / 4 h / 20 °C

With sodium hydroxide; lithium aluminium tetrahydride; copper(II) bis(trifluoromethanesulfonate); Dess-Martin periodane; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; 3: Dess-Martin oxidation;
DOI:10.1021/jm0499209

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 695171-96-1
diphenyl benzyloxycarbonylamino-(4-(tert-butyloxycarbonylaminomethyl)phenyl)methanephosphonate

Guidance literature:: Multi-step reaction with 4 steps

1: aq. NaOH / dioxane / 20 °C

2: 86 percent / LiAlH₄ / dioxane; tetrahydrofuran

3: 79 percent / Dess-Martin periodane / CH₂Cl₂ / 3 h / 20 °C

4: 39 percent / Cu(OTf)2 / methanol / 4 h / 20 °C

With sodium hydroxide; lithium aluminium tetrahydride; copper(II) bis(trifluoromethanesulfonate); Dess-Martin periodane; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; 3: Dess-Martin oxidation;
DOI:10.1021/jm0499209