2,6-Di-tert-butyl-4-diethylphosphorylmethylene-2,5-cyclohexadien-1-one

Base Information

• Chemical Name: 2,6-Di-tert-butyl-4-diethylphosphorylmethylene-2,5-cyclohexadien-1-one
• CAS No.: 135347-59-0
• Molecular Formula: C₁₉H₃₁O₂P
• Molecular Weight: 322.428
• Mol file: 135347-59-0.mol

Synonyms:2,6-Di-tert-butyl-4-diethylphosphorylmethylene-2,5-cyclohexadien-1-one

Chemical Property of 2,6-Di-tert-butyl-4-diethylphosphorylmethylene-2,5-cyclohexadien-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-Di-tert-butyl-4-diethylphosphorylmethylene-2,5-cyclohexadien-1-one

There total 4 articles about 2,6-Di-tert-butyl-4-diethylphosphorylmethylene-2,5-cyclohexadien-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(4-hydroxy-3,5-di-tert-butylbenzyl)diethylphosphine oxide (135347-58-9) → 2,6-Di-tert-butyl-4-diethylphosphorylmethylene-2,5-cyclohexadien-1-one (135347-59-0)

Guidance literature:

With potassium hexacyanoferrate(III); In potassium hydroxide; benzene;

Reference yield: 76.0%

diethylchlorophosphine (686-69-1) + 4-hydroxy-3,5-di-tert-butylbenzylidene dichloride (19382-02-6) → 2,6-Di-tert-butyl-4-diethylphosphorylmethylene-2,5-cyclohexadien-1-one (135347-59-0)

Guidance literature:

diethylchlorophosphine; 4-hydroxy-3,5-di-tert-butylbenzylidene dichloride; In hexane; for 0.5h; Reflux;

With trimethyl orthoformate; In hexane; for 1h; Reflux;

DOI:10.1134/S1070363214110413

Reference yield:

N,N-dimethyl-(3,5-di-tert-butyl-4-hydroxybenzyl)amine (88-27-7) → 2,6-Di-tert-butyl-4-diethylphosphorylmethylene-2,5-cyclohexadien-1-one (135347-59-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 42 percent / 5 h / 170 - 190 °C

2: 95 percent / K₃Fe(CN)6 / benzene; aq. KOH

With potassium hexacyanoferrate(III); In potassium hydroxide; benzene;

upstream raw materials:

(4-hydroxy-3,5-di-tert-butylbenzyl)diethylphosphine oxide

N,N-dimethyl-(3,5-di-tert-butyl-4-hydroxybenzyl)amine

diethylchlorophosphine

4-hydroxy-3,5-di-tert-butylbenzylidene dichloride

Downstream raw materials:

3,5-Di-tert-butyl-4-hydroxy-α-phenylaminobenzyldiethylphosphine oxide

3,5-Di-tert-butyl-4-hydroxy-α-piperidinobenzyldiethylphosphine oxide