2-[4-(2-Methoxyphenyl)piperazino]ethanethioamide

Base Information

Chemical Name:2-[4-(2-Methoxyphenyl)piperazino]ethanethioamide
CAS No.:219125-59-4
Molecular Formula:C13H19 N3 O S
Molecular Weight:265.37
Hs Code.:
DSSTox Substance ID:DTXSID80372439
Wikidata:Q82160152
Mol file:219125-59-4.mol

Synonyms:2-[4-(2-methoxyphenyl)piperazino]ethanethioamide;219125-59-4;2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanethioamide;1-Piperazineethanethioamide,4-(2-methoxyphenyl)-;Maybridge1_007960;2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethanethioamide;Oprea1_734330;HMS564B18;DTXSID80372439;AKOS000183162;FT-0610869

Suppliers and Price of 2-[4-(2-Methoxyphenyl)piperazino]ethanethioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-[4-(2-METHOXYPHENYL)PIPERAZINO]ETHANETHIOAMIDE 95.00%
250MG
$ 659.74

Total 9 raw suppliers

Chemical Property of 2-[4-(2-Methoxyphenyl)piperazino]ethanethioamide

Chemical Property:

Vapor Pressure:2.12E-07mmHg at 25°C
Melting Point:130℃
Refractive Index:1.605
Boiling Point:424.1°Cat760mmHg
Flash Point:210.3°C
PSA：73.82000
Density:1.189g/cm³
LogP:1.80650
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:265.12488341
Heavy Atom Count:18
Complexity:279

Purity/Quality:

98% ^*data from raw suppliers

2-[4-(2-METHOXYPHENYL)PIPERAZINO]ETHANETHIOAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): R34:Causes burns.;
Hazard Codes: C:Corrosive;
Statements: R34:Causes burns.;
Safety Statements: S36:Wear suitable protective clothing.; S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.;

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1N2CCN(CC2)CC(=S)N

Technology Process of 2-[4-(2-Methoxyphenyl)piperazino]ethanethioamide

There total 2 articles about 2-[4-(2-Methoxyphenyl)piperazino]ethanethioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 219125-57-2
4-(2-methoxyphenyl)-1-piperazineacetamide

: 219125-59-4
4-(2-methoxyphenyl)-1-piperazinethioacetamide

Guidance literature:: With Lawessons reagent; In tetrahydrofuran; for 1h; Heating;
DOI:10.1021/jm981041x

Reference yield:

: 35386-24-4
1-(2-Methoxyphenyl)piperazine

: 219125-59-4
4-(2-methoxyphenyl)-1-piperazinethioacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / K₂CO₃ / toluene / Heating

2: 86 percent / Lawesson's reagent / tetrahydrofuran / 1 h / Heating

With Lawessons reagent; potassium carbonate; In tetrahydrofuran; toluene;
DOI:10.1021/jm981041x