(4-OXO-PIPERIDIN-1-YL)-ACETIC ACID HYDROCHLORIDE

Base Information

• Chemical Name: (4-OXO-PIPERIDIN-1-YL)-ACETIC ACID HYDROCHLORIDE
• CAS No.: 218772-96-4
• Molecular Formula: C7H11 N O3
• Molecular Weight: 157.169
• Hs Code.: 2933399090
• Mol file: 218772-96-4.mol

Synonyms:(4-OXO-PIPERIDIN-1-YL)-ACETIC ACID HYDROCHLORIDE

Chemical Property of (4-OXO-PIPERIDIN-1-YL)-ACETIC ACID HYDROCHLORIDE

Chemical Property:

• PSA: 57.61000
• LogP: -0.32620
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

(4-Oxo-piperidin-1-yl)-aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-OXO-PIPERIDIN-1-YL)-ACETIC ACID HYDROCHLORIDE

There total 2 articles about (4-OXO-PIPERIDIN-1-YL)-ACETIC ACID HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.2%

4-piperidone hydrochloride (41979-39-9) + chloroacetic acid (79-11-8) → 4-piperidon-1-acetic acid (218772-96-4)

Guidance literature:

With potassium carbonate; In water; at 60 - 75 ℃; for 6h; Reagent/catalyst; Temperature;

Reference yield:

bromoacetic acid tert-butyl ester (5292-43-3) + 4-piperidone monohydrochloride monohydrate (40064-34-4,320589-77-3) → 4-piperidon-1-acetic acid (218772-96-4)

Guidance literature:

With potassium carbonate; In N-methyl-acetamide;

Reference yield: 90.5%

4-piperidon-1-acetic acid (218772-96-4) → 2-(3,5-dichloro-4-oxopyridine-1(4H)-yl)acetic acid (56187-37-2)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide; In water; at 50 - 55 ℃; for 8h;

upstream raw materials:

bromoacetic acid tert-butyl ester

4-piperidone monohydrochloride monohydrate

4-piperidone hydrochloride

chloroacetic acid

Downstream raw materials:

2-(3,5-dichloro-4-oxopyridine-1(4H)-yl)acetic acid