1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-3,6-dihydro-1(2H)-pyridinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-3,6-dihydro-1(2H)-pyridinecarboxylate
CAS No.:645379-62-0
Molecular Formula:C₂₀H₂₅FN₂O₂
Molecular Weight:344.429
Hs Code.:

Synonyms:1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-3,6-dihydro-1(2H)-pyridinecarboxylate

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Chemical Property of 1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-3,6-dihydro-1(2H)-pyridinecarboxylate

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Technology Process of 1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-3,6-dihydro-1(2H)-pyridinecarboxylate

There total 1 articles about 1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-3,6-dihydro-1(2H)-pyridinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 645379-61-9
1,1-dimethylethyl-4-[2-cyano-3-(ethyloxy)-1-(4-fluoro-2-methylphenyl)-3-oxopropyl]-3,6-dihydro-1(2H)-pyridinecarboxylate

: 645379-62-0
1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-3,6-dihydro-1(2H)-pyridinecarboxylate

Guidance literature:: With water; sodium chloride; In dimethyl sulfoxide; at 160 ℃; for 2h;

Reference yield:

: 645379-62-0
1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-3,6-dihydro-1(2H)-pyridinecarboxylate

: 645379-63-1
3-(1-{[(1,1-dimethylethyl)oxy]carbonyl}-1,2,3,6-tetrahydro-4-pyridinyl)-3-(4-fluoro-2-methylphenyl)propanoic acid

Guidance literature:: 1,1-dimethylethyl-4-[2-cyano-1-(4-fluoro-2-methylphenyl)ethyl]-3,6-dihydro-1(2H)-pyridinecarboxylate; With potassium hydroxide; In ethanol; water; at 150 ℃; for 0.5h; under 4654.46 Torr;

With hydrogenchloride; In ethanol; water; at 20 ℃; pH=4 / 5; citrate-hydrochloric acid buffer solution;