(E)-methyl 2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoate

Base Information

Chemical Name:(E)-methyl 2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoate
CAS No.:1059175-67-5
Molecular Formula:C₁₅H₁₈F₂N₂O₃
Molecular Weight:312.316
Hs Code.:

Synonyms:(E)-methyl 2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoate

Suppliers and Price of (E)-methyl 2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-methyl 2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoate

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Technology Process of (E)-methyl 2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoate

There total 1 articles about (E)-methyl 2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 112897-97-9
(E)-3-(3,4-difluorophenyl)acrylic acid

: 4-aza-DL-leucine methyl ester dihydrochloride

: 1059175-67-5
(E)-methyl 2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

Reference yield:

: 1059175-67-5
(E)-methyl 2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoate

: (E)-2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoic acid hydrochloride

Guidance literature:: (E)-methyl 2-(3-(3,4-difluorophenyl)acrylamido)-3-(dimethylamino)propanoate; With methanol; sodium hydroxide; water; for 48h; Heating / reflux;

With hydrogenchloride; water; In methanol; pH=4.5;