Technology Process of C25H34O3Si
There total 4 articles about C25H34O3Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methyllithium;
With
copper(l) iodide;
In
diethyl ether;
at 0 ℃;
for 0.333333h;
Inert atmosphere;
(5R,6S)-6-(2-((tert-butyldiphenylsilyl)oxy)ethyl)-5-methyl-5,6-dihydro-2H-pyran-2-one;
In
diethyl ether;
at 0 ℃;
for 5h;
Inert atmosphere;
With
ammonium chloride;
In
diethyl ether; water;
Inert atmosphere;
DOI:10.1016/j.tet.2011.06.025
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 12 h / Inert atmosphere; Reflux
2.1: copper(l) iodide / diethyl ether / 0.33 h / 0 °C / Inert atmosphere
2.2: 5 h / 0 °C / Inert atmosphere
2.3: Inert atmosphere
With
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; copper(l) iodide;
In
diethyl ether; dichloromethane;
DOI:10.1016/j.tet.2011.06.025
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: toluene / 2 h / -78 °C / Inert atmosphere; Molecular sieve
1.2: 2 h / -78 - 20 °C / Inert atmosphere
2.1: dmap; N-ethyl-N,N-diisopropylamine / 18 h / 0 - 20 °C / Inert atmosphere
3.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 12 h / Inert atmosphere; Reflux
4.1: copper(l) iodide / diethyl ether / 0.33 h / 0 °C / Inert atmosphere
4.2: 5 h / 0 °C / Inert atmosphere
4.3: Inert atmosphere
With
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; dmap; copper(l) iodide; N-ethyl-N,N-diisopropylamine;
In
diethyl ether; dichloromethane; toluene;
DOI:10.1016/j.tet.2011.06.025
