1-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]ethan-1-one

Base Information

Chemical Name:1-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]ethan-1-one
CAS No.:217184-77-5
Molecular Formula:C13H9 F3 O S
Molecular Weight:270.275
Hs Code.:
DSSTox Substance ID:DTXSID20372357
Wikidata:Q82160024
Mol file:217184-77-5.mol

Synonyms:217184-77-5;1-[4-phenyl-5-(trifluoromethyl)-2-thienyl]ethan-1-one;1-[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]ethanone;Ethanone,1-[4-phenyl-5-(trifluoromethyl)-2-thienyl]-;1-(4-Phenyl-5-(trifluoromethyl)thiophen-2-yl)ethanone;HMS563M07;Maybridge1_007839;SCHEMBL1799551;DTXSID20372357;MFCD00098442;FT-0643994;1-[4-phenyl-5-(trifluoromethyl)-2-thienyl]ethanone;1-(4-phenyl-5-trifluoromethyl-thiophen-2-yl)-ethanone

Suppliers and Price of 1-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-[4-PHENYL-5-(TRIFLUOROMETHYL)-2-THIENYL]ETHAN-1-ONE 95.00%
5MG
$ 500.52

AHH
1-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]ethan-1-one 97%
25g
$ 298.00

Total 5 raw suppliers

Chemical Property of 1-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]ethan-1-one

Chemical Property:

Vapor Pressure:0.000148mmHg at 25°C
Refractive Index:1.526
Boiling Point:332.3°Cat760mmHg
Flash Point:154.7°C
PSA：45.31000
Density:1.291g/cm³
LogP:4.63650
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:270.03262057
Heavy Atom Count:18
Complexity:310

Purity/Quality:

97% ^*data from raw suppliers

1-[4-PHENYL-5-(TRIFLUOROMETHYL)-2-THIENYL]ETHAN-1-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=C(S1)C(F)(F)F)C2=CC=CC=C2

Technology Process of 1-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]ethan-1-one

There total 3 articles about 1-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 917-54-4
methyllithium

: 208108-76-3
(4-phenyl-5-trifluoromethyl)thiophene-2-carboxylic acid

: 217184-77-5
1-(4-phenyl-5-trifluoromethyl-thiophen-2-yl)-ethanone

Guidance literature:: In tetrahydrofuran; diethyl ether; at 20 ℃; for 0.166667h;

Reference yield:

: 350-92-5
1,1,1-Trifluoro-3-phenylpropan-2-one

: 217184-77-5
1-(4-phenyl-5-trifluoromethyl-thiophen-2-yl)-ethanone

Guidance literature:: Multi-step reaction with 4 steps

1.1: trichlorophosphate / 0.33 h / 0 - 20 °C

1.2: 20 h / 20 - 45 °C

2.1: sodium hydride / tetrahydrofuran / 0.5 h / -10 - 0 °C

2.2: 0.75 h / 20 °C

3.1: lithium hydroxide; ethanol; water / 2 h / 65 °C

4.1: tetrahydrofuran; diethyl ether / 0.17 h / 20 °C

With lithium hydroxide; ethanol; water; sodium hydride; trichlorophosphate; In tetrahydrofuran; diethyl ether;

Reference yield:

: 119197-24-9,119197-25-0,146936-34-7
3-chloro-4,4,4-trifluoro-2-phenyl-but-2-enal

: 217184-77-5
1-(4-phenyl-5-trifluoromethyl-thiophen-2-yl)-ethanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / tetrahydrofuran / 0.5 h / -10 - 0 °C

1.2: 0.75 h / 20 °C

2.1: lithium hydroxide; ethanol; water / 2 h / 65 °C

3.1: tetrahydrofuran; diethyl ether / 0.17 h / 20 °C

With lithium hydroxide; ethanol; water; sodium hydride; In tetrahydrofuran; diethyl ether;