5-Thiazolecarboxylicacid,2-[(aminoiminomethyl)amino]-4-methyl-(9CI)

Base Information

• Chemical Name: 5-Thiazolecarboxylicacid,2-[(aminoiminomethyl)amino]-4-methyl-(9CI)
• CAS No.: 216955-55-4
• Molecular Formula: C6H8 N4 O2 S
• Molecular Weight: 200.22
• Hs Code.: 2934100090
• Mol file: 216955-55-4.mol

Synonyms:5-Thiazolecarboxylicacid,2-[(aminoiminomethyl)amino]-4-methyl-(9CI)

Chemical Property of 5-Thiazolecarboxylicacid,2-[(aminoiminomethyl)amino]-4-methyl-(9CI)

Chemical Property:

• PSA: 128.84000
• LogP: 1.36400

Purity/Quality:

99% ^*data from raw suppliers

2-{[Amino(imino)methyl]amino}-4-methyl-1,3-thiazole-5-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Thiazolecarboxylicacid,2-[(aminoiminomethyl)amino]-4-methyl-(9CI)

There total 2 articles about 5-Thiazolecarboxylicacid,2-[(aminoiminomethyl)amino]-4-methyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-guanidino-4-methyl-thiazole-5-carboxylic acid ethyl ester; monohydrochloride (131184-96-8) → 2-guanidino-4-methyl-thiazole-5-carboxylic acid (216955-55-4)

Guidance literature:

With sodium hydroxide; acetic acid; In ethanol;

Reference yield:

ethyl 4-methyl-2-guanidino-5-thiazolylcarboxylate hydrochloride → 2-guanidino-4-methyl-thiazole-5-carboxylic acid (216955-55-4)

Guidance literature:

Reference yield:

ethyl 2-(4-aminophenoxy)ethanoate hydrochloride (6973-42-8) + 2-guanidino-4-methyl-thiazole-5-carboxylic acid (216955-55-4) → ethyl {4-[(2-guanidino-4-methyl-thiazole-5-carbonyl)-amino]-phenoxy}-acetate

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In N,N-dimethyl-formamide;

upstream raw materials:

2-guanidino-4-methyl-thiazole-5-carboxylic acid ethyl ester; monohydrochloride

Downstream raw materials:

ethyl rac 3-[2-[cyclopropyl-(2-guanidino-4-methyl-thiazol-5-yl-carbonyl)amino]-acetylamino]-3-phenyl-propionate hydrochloride

ethyl rac-3-[3-[(2-guanidino-4-methyl-thiazol-5-yl-carbonyl)-amino]benzenesulphonylamino]-3-phenyl-propionate

ethyl (RS)-3-[5-[(2-guanidino-4-methyl-thiazol-5-carbonyl)-amino]-2-(2-methoxy-ethoxy)-benzoylamino]-3-phenyl-propionate

ethyl (RS)-3-{3-benzyloxy-5-[(2-guanidino-4-methyl-thiazol-5-carbonyl)-amino]-benzoylamino}-3-phenyl-propionate

Refernces

• 1、 -. "Thiazole derivatives". . . Retrieved 2008/06/13.