2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride

Base Information

Chemical Name:2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride
CAS No.:1174044-39-3
Molecular Formula:C₁₅H₁₇ClFNO₃
Molecular Weight:313.756
Hs Code.:

Synonyms:2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride

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Chemical Property of 2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride

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Technology Process of 2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride

There total 1 articles about 2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1174044-31-5
2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid

: 1174044-39-3
2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride

Guidance literature:: With 1-chloro-1-(dimethylamino)-2-methyl-1-propene; In dichloromethane; at 0 ℃; for 2h; Product distribution / selectivity;

Reference yield: 76.0%

: 69687-80-5
methyl 2,5-dimethyl-1H-pyrrole-3-carboxylate

: 1174044-39-3
2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride

: 1174044-40-6
methyl 4-(2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate

Guidance literature:: methyl 2,5-dimethyl-1H-pyrrole-3-carboxylate; With aluminum (III) chloride; In dichloromethane; at 0 ℃; for 0.166667h;

2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride; In dichloromethane; at 0 - 20 ℃;

Reference yield: 41.5%

: 40611-76-5
methyl 5-methyl-1H-pyrrole-3-carboxylate

: 1174044-39-3
2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride

: 1174044-42-8
methyl 4-(2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetyl)-5-methyl-1H-pyrrole-3-carboxylate

Guidance literature:: methyl 5-methyl-1H-pyrrole-3-carboxylate; With aluminum (III) chloride; In DCM; at 0 ℃; for 0.166667h;

2-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl)acetic acid chloride; In dichloromethane; at 0 - 20 ℃;

With aluminum (III) chloride; In dichloromethane; at 20 ℃; for 1h;