6-(2-Methoxypyrimidin-5-yl)-nicotinic acid

Base Information

• Chemical Name: 6-(2-Methoxypyrimidin-5-yl)-nicotinic acid
• CAS No.: 216867-60-6
• Molecular Formula: C₁₁H₈N₂O₂
• Molecular Weight: 200.197
• Hs Code.: 2933399090
• Mol file: 216867-60-6.mol

Synonyms:6-(2-Methoxypyrimidin-5-yl)-nicotinic acid;6-(Pyridin-4-yl)-nicotinic acid;6-(Pyrimidin-5-yl)-nicotinic acid

Chemical Property of 6-(2-Methoxypyrimidin-5-yl)-nicotinic acid

Chemical Property:

• PSA: 85.20000
• LogP: 1.24540
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

[2,4'-Bipyridine]-5-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-(2-Methoxypyrimidin-5-yl)-nicotinic acid

There total 2 articles about 6-(2-Methoxypyrimidin-5-yl)-nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-methyl-2,4'-bipyridine (106047-21-6) → 6-(pyridin-4-yl)nicotinic acid (216867-60-6)

Guidance literature:

With potassium permanganate;

DOI:10.1039/c2ce05948g

Reference yield:

methyl 6-(4-pyridyl)nicotinate → 6-(pyridin-4-yl)nicotinic acid (216867-60-6)

Guidance literature:

upstream raw materials:

5-methyl-2,4'-bipyridine