Cyclopropanecarboxaldehyde, 2-(1Z)-1-hexenyl-, (1S,2S)- (9CI)

Base Information

Chemical Name:Cyclopropanecarboxaldehyde, 2-(1Z)-1-hexenyl-, (1S,2S)- (9CI)
CAS No.:216862-78-1
Molecular Formula:C₁₀H₁₆O
Molecular Weight:152.236
Hs Code.:
Mol file:216862-78-1.mol

Synonyms:Cyclopropanecarboxaldehyde,2-(1Z)-1-hexenyl-, (1S,2S)- (9CI)

Suppliers and Price of Cyclopropanecarboxaldehyde, 2-(1Z)-1-hexenyl-, (1S,2S)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of Cyclopropanecarboxaldehyde, 2-(1Z)-1-hexenyl-, (1S,2S)- (9CI)

Chemical Property:

PSA：17.07000
LogP:2.56780

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclopropanecarboxaldehyde, 2-(1Z)-1-hexenyl-, (1S,2S)- (9CI)

There total 5 articles about Cyclopropanecarboxaldehyde, 2-(1Z)-1-hexenyl-, (1S,2S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 106137-60-4
(1S,2S)-2-<(Z)-hex-1-enyl>cyclopropane-1-methanol

: 216862-78-1
(1S,2S)-2-<(Z)-hex-1-enyl>cyclopropane-1-carbaldehyde

Guidance literature:: With molecular sieve; sodium acetate; pyridinium chlorochromate; In dichloromethane; for 1h; Ambient temperature;
DOI:10.1002/(SICI)1522-2675(19981007)81:10<1754::AID-HLCA1754>3.0.CO;2-V

Reference yield:

: 158918-31-1
methyl (1S)-2-(diethoxymethyl)cycloprop-2-ene-1-carboxylate

: 216862-78-1
(1S,2S)-2-<(Z)-hex-1-enyl>cyclopropane-1-carbaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / hydrogen / 10 percent Pd/C / methanol / 0.25 h / 20 °C

2: 85 percent / 2N HCl / tetrahydrofuran / 2 h / 20 °C

3: 1) NaHMDS, 2) HMPA / 1) THF, hexane, -30 deg C then 15 deg C, 20 min, 2) THF, hexane, -50 deg, 10 min, C, 3) THF, hexane, -78 deg C, 20 min

4: 90 percent / DIBAL-H / diethyl ether; hexane / 2 h / -50 °C

5: 87 percent / PCC, mol. sieves, NaOAc / CH₂Cl₂ / 1 h / Ambient temperature

With hydrogenchloride; N,N,N,N,N,N-hexamethylphosphoric triamide; molecular sieve; hydrogen; sodium acetate; sodium hexamethyldisilazane; diisobutylaluminium hydride; pyridinium chlorochromate; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane;
DOI:10.1002/(SICI)1522-2675(19981007)81:10<1754::AID-HLCA1754>3.0.CO;2-V

Reference yield:

: 216862-74-7
methyl (1S,2R)-2-(diethoxymethyl)cyclopropane-1-carboxylate

: 216862-78-1
(1S,2S)-2-<(Z)-hex-1-enyl>cyclopropane-1-carbaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / 2N HCl / tetrahydrofuran / 2 h / 20 °C

2: 1) NaHMDS, 2) HMPA / 1) THF, hexane, -30 deg C then 15 deg C, 20 min, 2) THF, hexane, -50 deg, 10 min, C, 3) THF, hexane, -78 deg C, 20 min

3: 90 percent / DIBAL-H / diethyl ether; hexane / 2 h / -50 °C

4: 87 percent / PCC, mol. sieves, NaOAc / CH₂Cl₂ / 1 h / Ambient temperature

With hydrogenchloride; N,N,N,N,N,N-hexamethylphosphoric triamide; molecular sieve; sodium acetate; sodium hexamethyldisilazane; diisobutylaluminium hydride; pyridinium chlorochromate; In tetrahydrofuran; diethyl ether; hexane; dichloromethane;
DOI:10.1002/(SICI)1522-2675(19981007)81:10<1754::AID-HLCA1754>3.0.CO;2-V