[1,2-bis(dicyclohexylphosphino)ethane][(2,3-η)-naphthalyne]nickel(0)

Base Information

• Chemical Name: [1,2-bis(dicyclohexylphosphino)ethane][(2,3-η)-naphthalyne]nickel(0)
• CAS No.: 163557-05-9
• Molecular Formula: C₃₆H₅₄NiP₂
• Molecular Weight: 607.462
• Mol file: 163557-05-9.mol

Synonyms:[1,2-bis(dicyclohexylphosphino)ethane][(2,3-η)-naphthalyne]nickel(0)

Chemical Property of [1,2-bis(dicyclohexylphosphino)ethane][(2,3-η)-naphthalyne]nickel(0)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [1,2-bis(dicyclohexylphosphino)ethane][(2,3-η)-naphthalyne]nickel(0)

There total 2 articles about [1,2-bis(dicyclohexylphosphino)ethane][(2,3-η)-naphthalyne]nickel(0) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.2%

cis-bromo[1,2-bis(dicyclohexylphosphino)ethane][3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene-2-yl]nickel(II) → [1,2-bis(dicyclohexylphosphino)ethane][(2,3-η)-naphthalyne]nickel(0) (163557-05-9)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 0.166667h; Inert atmosphere;

DOI:10.1021/acs.orglett.6b02831

Reference yield: 44.0%

Ni(Br)(C10H6Br)(((C6H11)2PCH2)2) (163557-04-8) → [1,2-bis(dicyclohexylphosphino)ethane][(2,3-η)-naphthalyne]nickel(0) (163557-05-9)

Guidance literature:

With 1percent sodium amalgam; In tetrahydrofuran; Ar-atmosphere; stirring (25°C, 3 h); decanting, evapn., extg. (toluene), filtering, evapn. (vac.), washing (hexane), THF addn., pptn. on hexane addn. (-20°C);

Reference yield:

[1,2-bis(dicyclohexylphosphino)ethane][(2,3-η)-naphthalyne]nickel(0) (163557-05-9) → methyl 2-naphthyl ketone (93-08-3)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 1 h / 20 °C / Molecular sieve; Inert atmosphere

2: trifluoroacetic acid / dichloromethane / 0.5 h / 0 - 20 °C / Inert atmosphere

With trifluoroacetic acid; In dichloromethane;

DOI:10.1021/acs.orglett.6b02831

upstream raw materials:

Ni(Br)(C₁₀H₆Br)(((C₆H₁₁)2PCH₂)2)

Downstream raw materials:

2-Methylnaphthalene

methyl 2-naphthyl ketone