4-Thiazolecarboxylicacid,2-[(1S)-1-aminoethyl]-,ethylester(9CI)

Base Information

Chemical Name:4-Thiazolecarboxylicacid,2-[(1S)-1-aminoethyl]-,ethylester(9CI)
CAS No.:216480-96-5
Molecular Formula:C8H12 N2 O2 S
Molecular Weight:200.261
Hs Code.:
Mol file:216480-96-5.mol

Synonyms:4-Thiazolecarboxylicacid,2-[(1S)-1-aminoethyl]-,ethylester(9CI)

Suppliers and Price of 4-Thiazolecarboxylicacid,2-[(1S)-1-aminoethyl]-,ethylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-Ethyl2-(1-aminoethyl)thiazole-4-carboxylate 97%
1g
$ 804.00

Alichem
4-Thiazolecarboxylicacid,2-[(1s)-1-aminoethyl]-,ethylester
1g
$ 876.96

Total 1 raw suppliers

Chemical Property of 4-Thiazolecarboxylicacid,2-[(1S)-1-aminoethyl]-,ethylester(9CI)

Chemical Property:

PSA：93.45000
LogP:2.03980

Purity/Quality:: (S)-Ethyl2-(1-aminoethyl)thiazole-4-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Thiazolecarboxylicacid,2-[(1S)-1-aminoethyl]-,ethylester(9CI)

There total 4 articles about 4-Thiazolecarboxylicacid,2-[(1S)-1-aminoethyl]-,ethylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 96929-06-5
ethyl 2-<(S)-1-(N-t-butoxycarbonyl)aminoethyl>thiazole-4-carboxylate

: 216480-96-5
(S)-ethyl 2-(1-acetamidoethyl)thiazole-4-carboxylate

Guidance literature:: With trifluoroacetic acid; In methoxybenzene; at 0 ℃;
DOI:10.1002/(SICI)1521-4184(19999)332:9<297::AID-ARDP297>3.0.CO;2-#

Reference yield:

: 70-23-5
ethyl Bromopyruvate

: 216480-96-5
(S)-ethyl 2-(1-acetamidoethyl)thiazole-4-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: KHCO₃ / 1,2-dimethoxy-ethane / 0.02 h

2: trifluoroacetic anhydride; pyridine / 1,2-dimethoxy-ethane / 0 - 20 °C

3: TFA / methoxybenzene / 0 °C

With pyridine; potassium hydrogencarbonate; trifluoroacetic acid; trifluoroacetic anhydride; In 1,2-dimethoxyethane; methoxybenzene; 1: Cyclization / 2: Dehydration / 3: Decarboxylation;
DOI:10.1002/(SICI)1521-4184(19999)332:9<297::AID-ARDP297>3.0.CO;2-#

Reference yield:

: 1025830-13-0
2-((S)-1-tert-Butoxycarbonylamino-ethyl)-4-hydroxy-4,5-dihydro-thiazole-4-carboxylic acid ethyl ester

: 216480-96-5
(S)-ethyl 2-(1-acetamidoethyl)thiazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic anhydride; pyridine / 1,2-dimethoxy-ethane / 0 - 20 °C

2: TFA / methoxybenzene / 0 °C

With pyridine; trifluoroacetic acid; trifluoroacetic anhydride; In 1,2-dimethoxyethane; methoxybenzene; 1: Dehydration / 2: Decarboxylation;
DOI:10.1002/(SICI)1521-4184(19999)332:9<297::AID-ARDP297>3.0.CO;2-#