1-[N²-[3,5-dibromo-N-[[[2-(2-methoxyphenyl)ethyl]-amino]carbonyl]-D-tyrosyl]-N⁶-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine

Base Information

• Chemical Name: 1-[N²-[3,5-dibromo-N-[[[2-(2-methoxyphenyl)ethyl]-amino]carbonyl]-D-tyrosyl]-N⁶-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine
• CAS No.: 204694-69-9
• Molecular Formula: C₄₂H₄₉Br₂N₇O₇
• Molecular Weight: 923.702

Synonyms:1-[N²-[3,5-dibromo-N-[[[2-(2-methoxyphenyl)ethyl]-amino]carbonyl]-D-tyrosyl]-N⁶-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine

Chemical Property of 1-[N²-[3,5-dibromo-N-[[[2-(2-methoxyphenyl)ethyl]-amino]carbonyl]-D-tyrosyl]-N⁶-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[N²-[3,5-dibromo-N-[[[2-(2-methoxyphenyl)ethyl]-amino]carbonyl]-D-tyrosyl]-N⁶-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine

There total 7 articles about 1-[N²-[3,5-dibromo-N-[[[2-(2-methoxyphenyl)ethyl]-amino]carbonyl]-D-tyrosyl]-N⁶-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

2-methoxyphenethyl isocyanate + 1-[N2-(3,5-dibromo-D-tyrosyl)-N6-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine (204693-53-8) → 1-[N2-[3,5-dibromo-N-[[[2-(2-methoxyphenyl)ethyl]-amino]carbonyl]-D-tyrosyl]-N6-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine (204694-69-9)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 72h;

DOI:10.1021/jm0490641

Reference yield:

N-[(1,1-dimethylethoxy)carbonyl]-3,5-dibromo-D-tyrosine (349535-07-5) → 1-[N2-[3,5-dibromo-N-[[[2-(2-methoxyphenyl)ethyl]-amino]carbonyl]-D-tyrosyl]-N6-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine (204694-69-9)

Guidance literature:

Multi-step reaction with 3 steps

1: diisopropylethylamine; TBTU; HOBt / dimethylformamide / 20 °C

2: trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

3: 40 percent / tetrahydrofuran / 72 h / 20 °C

With benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm0490641

Reference yield:

1-[N6-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine (204692-58-0) → 1-[N2-[3,5-dibromo-N-[[[2-(2-methoxyphenyl)ethyl]-amino]carbonyl]-D-tyrosyl]-N6-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine (204694-69-9)

Guidance literature:

Multi-step reaction with 3 steps

1: diisopropylethylamine; TBTU; HOBt / dimethylformamide / 20 °C

2: trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

3: 40 percent / tetrahydrofuran / 72 h / 20 °C

With benzotriazol-1-ol; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm0490641

upstream raw materials:

1-[N²-(3,5-dibromo-D-tyrosyl)-N⁶-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine

N-[(1,1-dimethylethoxy)carbonyl]-3,5-dibromo-D-tyrosine

1-[N⁶-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine

1-[N²-(1,1-dimethylethoxycarbonyl)-N⁶-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 204694-69-9 1-[N²-[3,5-dibromo-N-[[[2-(2-methoxyphenyl)ethyl]-amino]carbonyl]-D-tyrosyl]-N⁶-(phenylmethoxycarbonyl)-L-lysyl]-4-(4-pyridinyl)piperazine

Send

Send

Metric Ton KG G Pound L ML

Send

Send