3H-Pyrrolizin-3-one,hexahydro-5,6-bis(methylene)-,(7aS)-(9CI)

Base Information

Chemical Name:3H-Pyrrolizin-3-one,hexahydro-5,6-bis(methylene)-,(7aS)-(9CI)
CAS No.:216172-36-0
Molecular Formula:C₉H₁₁NO
Molecular Weight:149.192
Hs Code.:
Mol file:216172-36-0.mol

Synonyms:3H-Pyrrolizin-3-one,hexahydro-5,6-bis(methylene)-,(7aS)-(9CI)

Suppliers and Price of 3H-Pyrrolizin-3-one,hexahydro-5,6-bis(methylene)-,(7aS)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3H-Pyrrolizin-3-one,hexahydro-5,6-bis(methylene)-,(7aS)-(9CI)

Chemical Property:

PSA：0.00000
LogP:0.00000

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3H-Pyrrolizin-3-one,hexahydro-5,6-bis(methylene)-,(7aS)-(9CI)

There total 3 articles about 3H-Pyrrolizin-3-one,hexahydro-5,6-bis(methylene)-,(7aS)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 591-50-4
iodobenzene

: 216172-25-7
(S)-5-[2-(4-tert-Butyl-phenoxymethyl)-buta-2,3-dienyl]-pyrrolidin-2-one

: 216172-36-0
(S)-5,6-Dimethylene-hexahydro-pyrrolizin-3-one

: (S)-5-Benzyl-6-(4-tert-butyl-phenoxymethyl)-1,2,7,7a-tetrahydro-pyrrolizin-3-one

Guidance literature:: With tetrabutyl-ammonium chloride; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In acetonitrile; for 3h; Heating;
DOI:10.1055/s-1998-1859

Reference yield: 7.0%

: 216172-25-7
(S)-5-[2-(4-tert-Butyl-phenoxymethyl)-buta-2,3-dienyl]-pyrrolidin-2-one

: 216172-36-0
(S)-5,6-Dimethylene-hexahydro-pyrrolizin-3-one

: (S)-5-Benzyl-6-(4-tert-butyl-phenoxymethyl)-1,2,7,7a-tetrahydro-pyrrolizin-3-one

Guidance literature:: With iodobenzene; tetrabutyl-ammonium chloride; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In acetonitrile; at 80 ℃; for 3h;
DOI:10.1055/s-1998-1859

Reference yield:

: 29266-73-7
(-)-(S)-5-iodomethyl-2-pyrrolidinone

: 216172-36-0
(S)-5,6-Dimethylene-hexahydro-pyrrolizin-3-one

Guidance literature:: Multi-step reaction with 2 steps

2: 50 percent / K₂CO₃, Bu₄NCl / Pd(PPh₃)4 / acetonitrile / 3 h / Heating

With tetrabutyl-ammonium chloride; potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In acetonitrile;
DOI:10.1055/s-1998-1859