Technology Process of (S)-2-Benzyloxycarbonylamino-6-oxo-heptanedioic acid dimethyl ester
There total 8 articles about (S)-2-Benzyloxycarbonylamino-6-oxo-heptanedioic acid dimethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Dess-Martin periodane;
In
dichloromethane;
at 20 ℃;
for 1.5h;
DOI:10.1021/ja960640v
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 95 percent / aq. LiOH / 12 h / 38 °C / porcine kidney acylase I
2: aq. K2CO3
3: 0.17 h
4: 1.) SnCl4 / 1.) CH2Cl2, -55 deg C, 10 min, 2.) CH2Cl2, -23 deg C, 4 h
5: 99 percent / H2, CHCl3 / 10percent Pd/C / methanol / 24 h / 760 Torr
6: 84 percent / pyridine / 90 h / 20 °C
7: 56 percent / Dess-Martin periodinane / CH2Cl2 / 1.5 h / 20 °C
With
pyridine; lithium hydroxide; chloroform; hydrogen; tin(IV) chloride; potassium carbonate; Dess-Martin periodane;
palladium on activated charcoal;
In
methanol; dichloromethane;
DOI:10.1021/ja960640v
- Guidance literature:
-
Multi-step reaction with 6 steps
1: aq. K2CO3
2: 0.17 h
3: 1.) SnCl4 / 1.) CH2Cl2, -55 deg C, 10 min, 2.) CH2Cl2, -23 deg C, 4 h
4: 99 percent / H2, CHCl3 / 10percent Pd/C / methanol / 24 h / 760 Torr
5: 84 percent / pyridine / 90 h / 20 °C
6: 56 percent / Dess-Martin periodinane / CH2Cl2 / 1.5 h / 20 °C
With
pyridine; chloroform; hydrogen; tin(IV) chloride; potassium carbonate; Dess-Martin periodane;
palladium on activated charcoal;
In
methanol; dichloromethane;
DOI:10.1021/ja960640v
![dimethyl (2RS,6S)-2-hydroxy-6-[N-(benzyloxycarbonyl)-amino]heptane-1,7-dioate](/Databaselist/images/loading.webp)
