SB-237376 free base

Base Information

• Chemical Name: SB-237376 free base
• CAS No.: 179258-59-4
• Molecular Formula: C₂₀H₂₅N₃O₅
• Molecular Weight: 387.436
• UNII: JED8M29NSU
• Wikidata: Q27281473
• Pharos Ligand ID: 8G3XKJVZ42SB
• ChEMBL ID: CHEMBL184461

Synonyms:(N-(3-((2-(3,4-dimethoxyphenyl)ethyl)ethyl)amino)propyl) -4-nitrobenzamide hydrochloride;SB-237376

Chemical Property of SB-237376 free base

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 10
• Exact Mass: 387.17942091
• Heavy Atom Count: 28
• Complexity: 477

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)CCNCCCNC(=O)C2=CC=C(C=C2)[N+](=O)[O-])OC

Technology Process of SB-237376 free base

There total 1 articles about SB-237376 free base which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-3-chloropropyl-4-nitrobenzamide (179258-63-0) + 2-(3,4-dimethoxyphenyl)-ethylamine (120-20-7) → N-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-4-nitrobenzamide (179258-59-4)

Guidance literature:

With triethylamine; In acetonitrile; at 50 ℃; for 15h;

DOI:10.1016/S0968-0896(98)00166-7

Reference yield:

N-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-4-nitrobenzamide (179258-59-4) → C20H23(3)H2N3O5

Guidance literature:

With tritium; BF4; In dichloromethane; at 20 ℃;

DOI:10.1002/(SICI)1099-1344(199908)42:8<797::AID-JLCR240>3.0.CO;2-O

Reference yield:

N-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-4-nitrobenzamide (179258-59-4) → N-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-4-nitro benzamide hydrochloride (179258-62-9)

Guidance literature:

With hydrogenchloride;

DOI:10.1016/S0968-0896(98)00166-7

upstream raw materials:

N-3-chloropropyl-4-nitrobenzamide

2-(3,4-dimethoxyphenyl)-ethylamine

Downstream raw materials:

N-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]propyl]-4-nitro benzamide hydrochloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 179258-59-4 N-[3-[[2-(3,4-dimethoxyphenyl)ethyl]amino]propyl]-4-nitrobenzamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send