allyl α-phenyl-2-aminophenethyl carbonate

Base Information

• Chemical Name: allyl α-phenyl-2-aminophenethyl carbonate
• CAS No.: 149913-87-1
• Molecular Formula: C₁₈H₁₉NO₃
• Molecular Weight: 297.354
• Mol file: 149913-87-1.mol

Synonyms:allyl α-phenyl-2-aminophenethyl carbonate

Chemical Property of allyl α-phenyl-2-aminophenethyl carbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of allyl α-phenyl-2-aminophenethyl carbonate

There total 4 articles about allyl α-phenyl-2-aminophenethyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 2.0%

α-phenyl-2-aminophenethyl alcohol (51308-10-2) + Allyl chloroformate (2937-50-0) → allyl α-phenyl-2-aminophenethyl carbonate (149913-87-1) + allyl α-phenyl-2-<(allyloxycarbonyl)amino>phenethyl carbonate (149913-91-7)

Guidance literature:

With pyridine; In diethyl ether; for 3h; Ambient temperature;

DOI:10.1002/jhet.5570290509

Reference yield:

1-methyl-2-nitrobenzene (88-72-2) → allyl α-phenyl-2-aminophenethyl carbonate (149913-87-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 73 percent / sodium ethoxide / dimethylsulfoxide / 24 h / Ambient temperature

2: 91 percent / iron powder, conc. hydrochloric acid / methanol; H₂O / 24 h / Heating

3: 81 percent / pyridine / diethyl ether / 3 h / Ambient temperature

With pyridine; hydrogenchloride; sodium ethanolate; iron; In methanol; diethyl ether; water; dimethyl sulfoxide;

DOI:10.1002/jhet.5570290509

Reference yield:

α-phenyl-2-nitrophenethyl alcohol (16764-13-9) → allyl α-phenyl-2-aminophenethyl carbonate (149913-87-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 91 percent / iron powder, conc. hydrochloric acid / methanol; H₂O / 24 h / Heating

2: 81 percent / pyridine / diethyl ether / 3 h / Ambient temperature

With pyridine; hydrogenchloride; iron; In methanol; diethyl ether; water;

DOI:10.1002/jhet.5570290509

upstream raw materials:

α-phenyl-2-aminophenethyl alcohol

Allyl chloroformate

1-methyl-2-nitrobenzene

α-phenyl-2-nitrophenethyl alcohol

Downstream raw materials:

2-phenyl-indole

Refernces