3-Iodo-benzoic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester

Base Information

• Chemical Name: 3-Iodo-benzoic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester
• CAS No.: 54055-98-0
• Molecular Formula: C₃₄H₅₁IO₂
• Molecular Weight: 618.682
• Mol file: 54055-98-0.mol

Synonyms:3-Iodo-benzoic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester

Chemical Property of 3-Iodo-benzoic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Iodo-benzoic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester

There total 1 articles about 3-Iodo-benzoic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Cholestanol (80-97-7) + 3-Iodobenzoic acid (618-51-9) → 3-Iodo-benzoic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester (54055-98-0)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1016/S0040-4039(00)02306-6

Reference yield: 90.0%

3-Iodo-benzoic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester (54055-98-0) → 3-Iodo-benzoic acid (3R,5S,8S,9R,10S,13R,14S,17R)-9-chloro-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester

Guidance literature:

With dichloro(4-nitrophenyl)-λ³-iodane; In dichloromethane; for 0.333333h; Ambient temperature; Irradiation;

Reference yield: 77.0%

3-Iodo-benzoic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester (54055-98-0) → cholest-9(11)-en-3α-ol (37772-32-0)

Guidance literature:

3-Iodo-benzoic acid (3R,5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester; With sulfuryl dichloride; dibenzoyl peroxide; In tetrachloromethane; for 2h; Heating;

With potassium hydroxide; In methanol; water; for 2h; Heating;

DOI:10.1016/S0040-4039(00)02306-6

upstream raw materials:

Cholestanol

3-Iodobenzoic acid

Downstream raw materials:

3-Iodo-benzoic acid (3R,9R,10S,13R,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-9-thiocyanato-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester

3-Iodo-benzoic acid (3R,10S,13R,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-2,3,4,5,6,7,8,10,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester

3-Iodo-benzoic acid (3R,9R,10S,13R,17R)-9-bromo-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester

3-Iodo-benzoic acid (3R,5S,8S,9R,10S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-9-thiocyanato-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester