2-Nitro-2-(4-hydroxy-3-methoxybenzyl)propionsaeureethylester

Base Information

• Chemical Name: 2-Nitro-2-(4-hydroxy-3-methoxybenzyl)propionsaeureethylester
• CAS No.: 82408-62-6
• Molecular Formula: C₁₃H₁₇NO₆
• Molecular Weight: 283.281
• Mol file: 82408-62-6.mol

Synonyms:2-Nitro-2-(4-hydroxy-3-methoxybenzyl)propionsaeureethylester

Chemical Property of 2-Nitro-2-(4-hydroxy-3-methoxybenzyl)propionsaeureethylester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-Nitro-2-(4-hydroxy-3-methoxybenzyl)propionsaeureethylester

There total 1 articles about 2-Nitro-2-(4-hydroxy-3-methoxybenzyl)propionsaeureethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

4-hydroxymethyl-2-methoxyphenol (498-00-0) + ethyl 2-nitropropionate (2531-80-8) → 2-Nitro-2-(4-hydroxy-3-methoxybenzyl)propionsaeureethylester (82408-62-6)

Guidance literature:

With potassium fluoride; tetrabutyl-ammonium chloride; In toluene; for 30h; Heating;

DOI:10.1002/ardp.19823150515

Reference yield:

2-Nitro-2-(4-hydroxy-3-methoxybenzyl)propionsaeureethylester (82408-62-6) → 3-0-Methyldopa (15073-80-0,6739-31-7)

Guidance literature:

With hydrogen; platinum(IV) oxide; nickel; Yield given. Multistep reaction; 1.) MeOH, reflux, 2.) MeOH;

DOI:10.1002/ardp.19823150515

upstream raw materials:

4-hydroxymethyl-2-methoxyphenol

ethyl 2-nitropropionate

Downstream raw materials:

3-0-Methyldopa