4-chloro-5-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)phthalonitrile

Base Information

• Chemical Name: 4-chloro-5-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)phthalonitrile
• CAS No.: 1312550-65-4
• Molecular Formula: C₂₄H₁₃ClN₂O₃
• Molecular Weight: 412.832
• Mol file: 1312550-65-4.mol

Synonyms:4-chloro-5-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)phthalonitrile

Chemical Property of 4-chloro-5-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)phthalonitrile

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-chloro-5-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)phthalonitrile

There total 1 articles about 4-chloro-5-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)phthalonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

7-hydroxy-3-methyl-4-phenyl-2H-chromen-2-one (54431-13-9) + 4,5-dichlorophthalonitrile (139152-08-2) → 4-chloro-5-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)phthalonitrile (1312550-65-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 48h; Inert atmosphere;

DOI:10.1016/j.ica.2011.03.066

Reference yield: 34.0%

4-chloro-5-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)phthalonitrile (1312550-65-4) + zinc(II) acetate dihydrate (5970-45-6) → octakis[2,9,16,23-(7-oxy-3-methyl-4-phenylcoumarin)-3,10,17,24-chloro]phthalocyaninato zinc(II) (1402543-70-7)

Guidance literature:

With 2-(N,N-dimethylamino)ethanol; for 24h; Reflux; Inert atmosphere;

DOI:10.1016/j.saa.2012.06.029

Reference yield: 27.0%

4-chloro-5-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)phthalonitrile (1312550-65-4) + indium(III) acetate → octakis[2,9,16,23-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)-3,10,17,24-chloro]phthalocyaninato indium(III) acetate

Guidance literature:

With N,N-dimethylaminoethanol; In further solvent(s); Ar; ligand and In(OAc)3 (1.21:0.65 mmol) in DMAE refluxed with stirring for 24 h; cooled to room temp., pptd. (MeOH), ppt. filtered off, washed (MeOH, EtOH, ethyl acetate, MeCN, acetone, Et2O), dried (vac.), chromd. (SiO2, CHCl3), elem. anal.;

DOI:10.1016/j.ica.2011.03.066

upstream raw materials:

7-hydroxy-3-methyl-4-phenyl-2H-chromen-2-one

4,5-dichlorophthalonitrile

Downstream raw materials:

octakis{[2,9,16,23-(3-methyl-2-oxo-4-phenyl-2H-chromen-7-yloxy)-3,10,17,24-chloro]}phthalocyaninato indium(III) acetate

octakis[2,9,16,23-(7-oxy-3-methyl-4-phenylcoumarin)-3,10,17,24-chloro]phthalocyaninato zinc(II)