(R)-2-Oxoimidazolidine-4-carboxylic Acid

Base Information

• Chemical Name: (R)-2-Oxoimidazolidine-4-carboxylic Acid
• CAS No.: 214767-15-4
• Molecular Formula: C4H6 N2 O3
• Molecular Weight: 130.1
• European Community (EC) Number: 858-214-2
• Mol file: 214767-15-4.mol

Synonyms:(R)-2-Oxoimidazolidine-4-carboxylic Acid;214767-15-4;(4R)-2-oxoimidazolidine-4-carboxylic acid;4-Imidazolidinecarboxylicacid,2-oxo-,(4R)-(9CI);SCHEMBL6602740;KZKRPYCBSZIQKN-UWTATZPHSA-N;MFCD00272205;(R)-2-Oxoimidazolidine-4-carboxylicacid;BS-51561;E74019;EN300-222145

Chemical Property of (R)-2-Oxoimidazolidine-4-carboxylic Acid

Chemical Property:

• PSA: 78.43000
• LogP: -0.59000
• XLogP3: -1.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 130.03784206
• Heavy Atom Count: 9
• Complexity: 156

Purity/Quality:

98% ^*data from raw suppliers

(R)-2-OXO-IMIDAZOLIDINE-4-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(NC(=O)N1)C(=O)O
• Isomeric SMILES: C1[C@@H](NC(=O)N1)C(=O)O

Technology Process of (R)-2-Oxoimidazolidine-4-carboxylic Acid

There total 1 articles about (R)-2-Oxoimidazolidine-4-carboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-2-oxoimidazolidine-1,5-dicarboxylic acid 1-benzyl ester (634614-25-8) → (R)-2-oxoimidazolidine-4-carboxylic acid (214767-15-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; methanol; at 20 ℃; for 24h; under 760.051 Torr;

Reference yield:

1-(4-fluorophenyl)-5-[3-fluoro-5-((R)-2,2,2-trifluoro-1-methylethoxymethyl)phenyl]-1H-pyrazol-3-ylamine (1426408-84-5) + (R)-2-oxoimidazolidine-4-carboxylic acid (214767-15-4) → (R)-2-oxoimidazolidine-4-carboxylic acid {1-(4-fluorophenyl)-5-[3-fluoro-5-((R)-2,2,2-trifluoro-1-methylethoxymethyl)phenyl]-1H-pyrazol-3-yl}amide (1426404-47-8)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In chloroform; at 20 ℃; for 3h;

Reference yield:

(R)-2-oxoimidazolidine-4-carboxylic acid (214767-15-4) + 5-(3-butylphenyl)-1-phenyl-1H-pyrazol-3-ylamine (1426408-95-8) → (R)-2-oxoimidazolidine-4-carboxylic acid [5-(3-butylphenyl)-1-phenyl-1H-pyrazol-3-yl]amide

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

upstream raw materials:

(R)-2-oxoimidazolidine-1,5-dicarboxylic acid 1-benzyl ester

Downstream raw materials:

(R)-2-oxoimidazolidine-4-carboxylic acid {1-(4-fluorophenyl)-5-[3-fluoro-5-((R)-2,2,2-trifluoro-1-methylethoxymethyl)phenyl]-1H-pyrazol-3-yl}amide

Refernces