BOC-P-CARBOXY-PHE(OTBU)-OH DCHA

Base Information

• Chemical Name: BOC-P-CARBOXY-PHE(OTBU)-OH DCHA
• CAS No.: 214750-69-3
• Molecular Formula: C19H27 N O6
• Molecular Weight: 365.426
• Mol file: 214750-69-3.mol

Synonyms:tert-Butyl4-((S)-2-tert-butoxycarbonylamino-2-carboxyethyl)benzoate

Chemical Property of BOC-P-CARBOXY-PHE(OTBU)-OH DCHA

Chemical Property:

• Boiling Point: 515.1±50.0 °C(Predicted)
• PKA: 3.78±0.10(Predicted)
• PSA: 113.96000
• Density: 1.156±0.06 g/cm3(Predicted)
• LogP: 7.18550
• Storage Temp.: -15°C

Purity/Quality:

≥ 98% (HPLC) ^*data from raw suppliers

Boc-(4--butyloxycarbonyl)-L-phenylalanine dicyclohexylammonium salt ≥ 98% (HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BOC-P-CARBOXY-PHE(OTBU)-OH DCHA

There total 6 articles about BOC-P-CARBOXY-PHE(OTBU)-OH DCHA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

C29H42N2O7S → 4-(2-tert-butoxycarbonylamino-2-carboxyethyl)benzoic acid tert-butyl ester (214750-69-3)

Guidance literature:

With lithium hydroxide; tetrabutylammomium bromide; lithium bromide; In acetonitrile; at 20 ℃; for 18h;

Reference yield:

4-[(S)-2-tert-Butoxycarbonylamino-3-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ6-thia-4-aza-tricyclo[5.2.1.01,5]dec-4-yl)-3-oxo-propyl]-benzoic acid tert-butyl ester → 4-(2-tert-butoxycarbonylamino-2-carboxyethyl)benzoic acid tert-butyl ester (214750-69-3)

Guidance literature:

With lithium hydroxide; tetrabutylammomium bromide; lithium bromide; In acetonitrile; at 20 ℃;

DOI:10.1021/jm0300680

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → 4-(2-tert-butoxycarbonylamino-2-carboxyethyl)benzoic acid tert-butyl ester (214750-69-3)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / dimethylformamide / 48 h / 20 °C

2: 6.2 g / LiOH; LiBr; nBu₄NBr / acetonitrile / 20 °C

With lithium hydroxide; tetrabutylammomium bromide; triethylamine; lithium bromide; In N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/jm0300680

upstream raw materials:

di-tert-butyl dicarbonate

4-(bromomethyl)benzoic acid 1,1-dimethylethyl ester

Downstream raw materials:

4-(2-tert-butoxycarbonylamino-3-methoxycarbonylpropyl)benzoic acid tert-butyl ester

4-[2-tert-butoxycarbonylamino-3-carboxy-3-(4-methoxybenzylsulfanyl)propyl]benzoic acid tert-butyl ester

4-[2-tert-butoxycarbonylamino-3-(4-methoxybenzylsulfanyl)-3-methoxycarbonylpropyl]benzoic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 214750-69-3 BOC-P-CARBOXY-PHE(OTBU)-OH DCHA

Send

Send

Metric Ton KG G Pound L ML

Send

Send