methyl 1,5-anhydro-6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-7-deoxy-2,3,4-tri-O-benzyl-α-D-manno-hept-6-enopyranose

Base Information

Chemical Name:methyl 1,5-anhydro-6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-7-deoxy-2,3,4-tri-O-benzyl-α-D-manno-hept-6-enopyranose
CAS No.:862730-77-6
Molecular Formula:C₄₂H₄₄O₉
Molecular Weight:692.806
Hs Code.:

Synonyms:methyl 1,5-anhydro-6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-7-deoxy-2,3,4-tri-O-benzyl-α-D-manno-hept-6-enopyranose

Suppliers and Price of methyl 1,5-anhydro-6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-7-deoxy-2,3,4-tri-O-benzyl-α-D-manno-hept-6-enopyranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 1,5-anhydro-6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-7-deoxy-2,3,4-tri-O-benzyl-α-D-manno-hept-6-enopyranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 1,5-anhydro-6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-7-deoxy-2,3,4-tri-O-benzyl-α-D-manno-hept-6-enopyranose

There total 4 articles about methyl 1,5-anhydro-6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-7-deoxy-2,3,4-tri-O-benzyl-α-D-manno-hept-6-enopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 862730-71-0
methyl 6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-2,3,4-tri-O-benzyl-α-D-mannuronic ester

: 862730-77-6
methyl 1,5-anhydro-6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-7-deoxy-2,3,4-tri-O-benzyl-α-D-manno-hept-6-enopyranose

Guidance literature:: With pyridine; In tetrahydrofuran; toluene; at -40 - 20 ℃; for 16h;
DOI:10.1016/j.tet.2005.05.032

Reference yield:

: 40653-15-4
methyl 2,3,4-tri-O-benzyl-α-D-manno-hexodialdo-1,5-pyranoside

: 862730-77-6
methyl 1,5-anhydro-6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-7-deoxy-2,3,4-tri-O-benzyl-α-D-manno-hept-6-enopyranose

Guidance literature:: Multi-step reaction with 3 steps

1: 488 mg / sodium chlorite; sodium dihydrogenphosphate; 2-methyl-2-butene / tetrahydrofuran; H₂O; 2-methyl-propan-2-ol / 16 h

2: 76 percent / N,N-dimethyl-4-aminopyridine; dicyclohexylcarbodiimide / CH₂Cl₂

3: 76 percent / pyridine / tetrahydrofuran; toluene / 16 h / -40 - 20 °C

With pyridine; dmap; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; water; toluene; tert-butyl alcohol; 3: Tebbe methylenation;
DOI:10.1016/j.tet.2005.05.032

Reference yield:

: 34212-64-1,641635-63-4
methyl 2,3,4-tri-O-benzyl-α-D-mannopyranoside

: 862730-77-6
methyl 1,5-anhydro-6-O-(4',6'-O-benzylidene-3'-O-yl-D-allal)-7-deoxy-2,3,4-tri-O-benzyl-α-D-manno-hept-6-enopyranose

Guidance literature:: Multi-step reaction with 4 steps

1: Dess-Martin periodinane / CH₂Cl₂ / 3 h

2: 488 mg / sodium chlorite; sodium dihydrogenphosphate; 2-methyl-2-butene / tetrahydrofuran; H₂O; 2-methyl-propan-2-ol / 16 h

3: 76 percent / N,N-dimethyl-4-aminopyridine; dicyclohexylcarbodiimide / CH₂Cl₂

4: 76 percent / pyridine / tetrahydrofuran; toluene / 16 h / -40 - 20 °C

With pyridine; dmap; sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; Dess-Martin periodane; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; water; toluene; tert-butyl alcohol; 4: Tebbe methylenation;
DOI:10.1016/j.tet.2005.05.032